SCHEMBL28005333

SCHEMBL28005333

CC(=O)C1(C#N)C=CC(c2ccccc2)=CC1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CTSS P25774 2/20 0.31
CTSK P43235 2/20 0.31
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CTSC P53634 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16486983 0.88 CTSL (0.31) CTSSCTSKCTSLCTSBCTSC
SCHEMBL21111928 0.85 MEN1 (0.35) MAPTSMN1; SMN2CTSSCTSKCTSL
SCHEMBL21111924 0.84 CTSL (0.31) CTSSCTSKCTSLCTSB
SCHEMBL29040153 0.83
SCHEMBL29027310 0.81 KDM4E (0.39) MAPTSMN1; SMN2
SCHEMBL8499526 0.81 MEN1 (0.36) MAPTSMN1; SMN2
SCHEMBL5479512 0.78 MAPT (0.35) MAPTSMN1; SMN2
SCHEMBL2428051 0.76 NOTUM (0.33)
SCHEMBL6808145 0.76 MAPT (0.33) MAPTSMN1; SMN2
SCHEMBL8486887 0.76 MAPT (0.33) MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118345390-A Method for preparing carbonyl compound by electrocatalytic oxidation of benzyl C-H bond by pyridine nitrogen oxide 浙江大学 2024-07-16 CN disclosed
CN-104603107-A Novel aromatic heterocyclic derivative, material for organic electroluminescent element, material solution for organic electroluminescent element, and organic electroluminescent element IDEMITSU KOSAN CO 2015-05-06 CN disclosed