Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28444641 | 0.87 | RARA (0.31) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL27641916 | 0.84 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2RARARARBRARG | |
| SCHEMBL27656088 | 0.84 | MEN1 (0.40) | MAPTMEN1KMT2A | |
| SCHEMBL28240002 | 0.83 | LMNA (0.33) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL5479512 | 0.81 | MAPT (0.35) | MAPTSMN1; SMN2AKR1C3RARARARB | |
| SCHEMBL29057754 | 0.81 | ALDH1A1 (0.33) | SMN1; SMN2 | |
| SCHEMBL28536651 | 0.81 | CES1 (0.32) | — | |
| SCHEMBL8502416 | 0.80 | FFAR1 (0.37) | MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6808145 | 0.78 | MAPT (0.33) | MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27604192 | 0.78 | MAPT (0.33) | MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640041-B | Method and system for preparing 4-bromodiphenyl and derivative thereof | 南京先进生物材料与过程装备研究院有限公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116640041-A | Method and system for preparing 4-bromodiphenyl and derivative thereof | 南京先进生物材料与过程装备研究院有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-112645823-B | Environment-friendly fluorine-containing surfactant and preparation method thereof | 绍兴市上虞区武汉理工大学高等研究院 | 2022-07-05 | — | — | CN | disclosed |
| CN-113999083-A | Novel method for synthesizing 2, 2-difluoroethyl aromatic compound | 山东理工大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-112645823-A | Environment-friendly fluorine-containing surfactant and preparation method thereof | 绍兴市上虞区武汉理工大学高等研究院 | 2021-04-13 | — | — | CN | disclosed |
| CN-100460385-C | Preparation method of 4-cyano-4' -hydroxybiphenyl | YANTAI VALIANT FINE CHEMICALS (CN) | 2009-02-11 | — | — | CN | disclosed |
| CN-1876623-A | Preparation method of 4-cyano-4' -hydroxybiphenyl | VALIANT FINE CHEMICALS CO LTD (CN) | 2006-12-13 | — | — | CN | disclosed |
| CN-1076345-C | 2,3-diaminopropionic acid derivative | SUMITOMO PHARMA (JP) | 2001-12-19 | — | — | CN | disclosed |
| WO-1999065899-A1 | NEW OXAZINYLAZOLE DERIVATIVES AS FUNGICIDES | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 1999-12-23 | — | — | WO | disclosed |
| CN-1080917-A | Biphenyl derivatives contains pharmaceutical composition of these compounds and preparation method thereof | THOMAE GMBH DR K (DE) | 1994-01-19 | — | — | CN | disclosed |