Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 3/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.47 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005275 | 0.87 | NFE2L2 (0.65) | EGFRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL28005280 | 0.81 | ALDH1A1 (0.54) | EGFRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL30969584 | 0.74 | MAPT (0.59) | EGFRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL16210587 | 0.74 | CYP26A1 (0.76) | EGFRALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL16210588 | 0.74 | CYP26A1 (0.76) | EGFRALDH1A1MEN1KMT2ACYP19A1 | |
| SCHEMBL28005693 | 0.74 | MAPT (0.59) | ALDH1A1CYP19A1XDHMAPTKDM4E | |
| SCHEMBL17077391 | 0.73 | EGFR (0.90) | EGFRXDHNFE2L2 | |
| SCHEMBL17077394 | 0.73 | EGFR (0.90) | EGFRXDHNFE2L2 | |
| SCHEMBL28005648 | 0.73 | POLB (0.61) | EGFRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL28005301 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1CYP19A1XDHMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592032-A | Asymmetric mono-carbonyl curcumin analogues having 2-nitro unilateral substitute and application of analogues | UNIV WENZHOU MEDICAL | 2015-05-06 | — | — | CN | disclosed |