Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 1/20 | 0.56 |
| ▸ | IL6 | P05231 | 1/20 | 0.56 |
| ▸ | MIF | P14174 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005646 | 0.82 | MEN1 (0.56) | POLBMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL28005275 | 0.81 | NFE2L2 (0.65) | POLBEGFRMEN1KMT2AMAPT | |
| SCHEMBL28005280 | 0.79 | ALDH1A1 (0.54) | POLBEGFRMEN1KMT2AMAPT | |
| SCHEMBL28005301 | 0.78 | SMN1; SMN2 (0.50) | MAPTCYP1A2CYP3A4CYP2C9MAOB | |
| SCHEMBL27912172 | 0.77 | MAPT (0.80) | POLBEGFRMEN1KMT2AMAPT | |
| SCHEMBL17077386 | 0.77 | EGFR (0.90) | POLBEGFRMEN1KMT2AMAPT | |
| SCHEMBL17077384 | 0.77 | EGFR (0.90) | POLBEGFRMEN1KMT2AMAPT | |
| SCHEMBL27930226 | 0.76 | MAPT (0.74) | POLBEGFRMEN1KMT2AMAPT | |
| SCHEMBL28005399 | 0.76 | HSD11B1 (0.69) | EGFRMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL1523848 | 0.75 | POLB (0.66) | POLBEGFRMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592032-A | Asymmetric mono-carbonyl curcumin analogues having 2-nitro unilateral substitute and application of analogues | UNIV WENZHOU MEDICAL | 2015-05-06 | — | — | CN | disclosed |