Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.48 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 4/20 | 0.47 |
| ▸ | FABP3 | P05413 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4256425 | 0.82 | FABP4 (0.65) | KDM4EAKR1C3AKR1C2CXCL8FABP4 | |
| SCHEMBL28005064 | 0.82 | FABP4 (0.56) | AKR1C3AKR1C2CXCL8FABP4FABP3 | |
| SCHEMBL6800630 | 0.81 | CTSV (0.53) | KDM4EAKR1C3AKR1C2CXCL8FABP4 | |
| SCHEMBL31633793 | 0.76 | CXCL8 (0.51) | KDM4ECXCL8FABP4FABP3MAPK8 | |
| SCHEMBL14576318 | 0.75 | GRIK1 (0.54) | KDM4EAKR1C3AKR1C2CXCL8FABP4 | |
| SCHEMBL16489007 | 0.75 | MAPT (0.62) | KDM4EAKR1C3AKR1C2FABP4FABP3 | |
| SCHEMBL22720122 | 0.74 | FABP4 (0.66) | KDM4EAKR1C3AKR1C2FABP4FABP3 | |
| SCHEMBL6141189 | 0.73 | FABP4 (0.62) | KDM4EAKR1C3AKR1C2FABP4FABP3 | |
| SCHEMBL30080395 | 0.73 | MAP2K1 (0.64) | KDM4EAKR1C3AKR1C2FABP4FABP3 | |
| SCHEMBL16571357 | 0.73 | MAP2K1 (0.64) | KDM4EAKR1C3AKR1C2FABP4FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103204825-B | Benzothiazole compounds as protein kinase inhibitors, and preparation method and application thereof | SHANGHAI KECHOW PHARMA INC | 2015-03-04 | — | — | CN | disclosed |