Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28005455

CC(C)NC1CCCCC1.O=C(O)C(F)(F)F

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK1 Q15118 1/20 0.43
PDK2 Q15119 1/20 0.43
PDK3 Q15120 1/20 0.43
PDK4 Q16654 1/20 0.43
ATM Q13315 1/20 0.42
EPHX1 P07099 10/20 0.40
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 1/20 0.39
CYP3A4 P08684 1/20 0.39
EPHX2 P34913 1/20 0.39
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7704610 0.84 ATM (0.47) ATMEPHX1ALDH1A1MEN1RECQL
Trifluoroacetic Acid SCHEMBL6826325 0.81 HTT (0.42) ALDH1A1MEN1RECQLKMT2ANPSR1
Trifluoroacetic Acid SCHEMBL6824506 0.81 HTT (0.42) ALDH1A1MEN1RECQLKMT2ANPSR1
Trifluoroacetic Acid SCHEMBL582998 0.79 ALDH1A1 (0.55) PDK1PDK2PDK3PDK4ATM
Trifluoromethanesulfonic Acid SCHEMBL28005079 0.79 PDK1 (0.39) PDK1PDK2PDK3PDK4ATM
SCHEMBL19705361 0.78 ALDH1A1 (0.47) ATMEPHX1ALDH1A1SMN1; SMN2NPC1
SCHEMBL18844888 0.78 ALDH1A1 (0.47) ATMEPHX1ALDH1A1SMN1; SMN2NPC1
SCHEMBL22369902 0.78 ALDH1A1 (0.47) ATMEPHX1ALDH1A1SMN1; SMN2NPC1
SCHEMBL7776775 0.78 ALDH1A1 (0.47) ATMEPHX1ALDH1A1SMN1; SMN2NPC1
SCHEMBL19966112 0.78 ALDH1A1 (0.47) ATMEPHX1ALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104342087-B N-isopropylcyclohexylamine-containing supramolecular phase material and preparation method and application thereof 厦门大学 2017-03-22 CN disclosed
CN-104342087-A N-isopropylcyclohexylamine-containing supramolecular phase material and preparation method and application thereof UNIV XIAMEN 2015-02-11 CN disclosed