Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005664 | 0.76 | CFD (0.41) | PTGS1HPGDNPC1KMT2AL3MBTL1 | |
| SCHEMBL12391548 | 0.76 | PTGER4 (0.47) | HPGDNPC1ACLYKMT2AL3MBTL1 | |
| SCHEMBL28796448 | 0.74 | PTGS1 (0.66) | PTGS1PTPN1PTPN2PTPN6ABCC4 | |
| SCHEMBL27769339 | 0.74 | PTGS1 (0.69) | PTGS1PTPN1PTPN2PTPN6HPGD | |
| SCHEMBL27769326 | 0.74 | PTGS1 (0.69) | PTGS1PTPN1PTPN2PTPN6KMT2A | |
| SCHEMBL28794195 | 0.73 | PTGS1 (0.64) | PTGS1PTPN1PTPN2PTPN6NR1H4 | |
| SCHEMBL13626646 | 0.73 | TACR3 (0.59) | HPGDNPC1ALDH1A1SMN1; SMN2IP6K1 | |
| SCHEMBL13626334 | 0.73 | ACMSD (0.60) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12024784 | 0.72 | NPC1 (0.49) | HPGDNPC1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL27748176 | 0.72 | PTGS1 (0.62) | PTGS1HPGDALDH1A1ABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214464-B | Tetrazole-substituted arylamides and application of tetrazole-substituted arylamides using as p2x3 and p2x2/3 receptor antagonists | HOFFMANN LA ROCHE | 2015-02-18 | — | — | CN | disclosed |