Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005665 | 0.76 | PTGS1 (0.59) | HPGDBRD4NPC1ALDH1A1RAB9A | |
| SCHEMBL1799221 | 0.76 | PTGS2 (0.59) | HPGDALDH1A1KDM4EESR1ITGB3 | |
| SCHEMBL28796445 | 0.74 | BACE1 (0.42) | CFDHPGDALDH1A1KDM4EESR1 | |
| SCHEMBL12391548 | 0.74 | PTGER4 (0.47) | HPGDNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27769325 | 0.74 | TDP1 (0.44) | CFDHPGDALDH1A1KDM4EESR1 | |
| SCHEMBL27769336 | 0.74 | TDP1 (0.44) | CFDHPGDALDH1A1KDM4EESR1 | |
| SCHEMBL27748175 | 0.73 | HDAC1 (0.52) | HPGDBRD4ALDH1A1KDM4EESR1 | |
| SCHEMBL28794193 | 0.73 | HDAC1 (0.41) | CFDHPGDALDH1A1KDM4EESR1 | |
| SCHEMBL13626646 | 0.71 | TACR3 (0.59) | HPGDBRD4NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13626334 | 0.71 | ACMSD (0.60) | NPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214464-B | Tetrazole-substituted arylamides and application of tetrazole-substituted arylamides using as p2x3 and p2x2/3 receptor antagonists | HOFFMANN LA ROCHE | 2015-02-18 | — | — | CN | disclosed |