Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25C | P30307 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28006132 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HPGDCDC25BMEN1KMT2A | |
| SCHEMBL28005825 | 0.82 | MEN1 (0.43) | ALDH1A1MEN1KMT2AMAPTDHODH | |
| SCHEMBL28005802 | 0.79 | VCP (0.43) | ALDH1A1MEN1KMT2AMAPTDHODH | |
| SCHEMBL28006082 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTDHODH | |
| SCHEMBL28006080 | 0.77 | KMT2A (0.44) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL852937 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HPGDCDC25BKMT2AKDM4E | |
| SCHEMBL28158769 | 0.73 | SMN1; SMN2 (0.42) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL29749080 | 0.71 | NR4A1 (0.47) | ALDH1A1HPGDCDC25BMEN1KMT2A | |
| SCHEMBL7833808 | 0.71 | NR4A1 (0.47) | ALDH1A1HPGDCDC25BMEN1KMT2A | |
| SCHEMBL28829235 | 0.70 | MEN1 (0.62) | ALDH1A1HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664625-B | 2,3,4,6-tetrasubstituted phenol derivative and preparation method thereof | UNIV EAST CHINA NORMAL | 2015-04-08 | — | — | CN | disclosed |