SCHEMBL28006148

SCHEMBL28006148

CCCc1ccc(-c2ccccc2-c2ccccc2)c(C)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 3/20 0.43
CD274 Q9NZQ7 3/20 0.43
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
DPP4 P27487 1/20 0.36
MAPT P10636 1/20 0.35
PPARA Q07869 1/20 0.35
FFAR4 Q5NUL3 1/20 0.34
ADRB2 P07550 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PTGS1 P23219 1/20 0.34
ELANE P08246 1/20 0.34
CTSG P08311 1/20 0.34
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9342239 0.91 PDCD1 (0.47) PDCD1CD274DPP4MAPTPPARA
SCHEMBL28006147 0.88 PDCD1 (0.44) PDCD1CD274DPP4MAPTPPARA
SCHEMBL8679942 0.81 PDCD1 (0.44) PDCD1CD274PTGS1ELANECTSG
SCHEMBL6546839 0.80 CD274 (0.67) PDCD1CD274CA12CA1CA2
SCHEMBL13685146 0.80 DPP4 (0.47) PDCD1CD274CA12CA1CA2
SCHEMBL8679266 0.76 CD274 (0.50) PDCD1CD274DPP4MAPTSMN1; SMN2
SCHEMBL607543 0.75 DPP4 (0.56) PDCD1CD274CA12CA1CA2
SCHEMBL11200440 0.75 PDCD1 (0.46) PDCD1CD274PTGS1
SCHEMBL11057507 0.74 ALDH1A1 (0.41) PDCD1CD274DPP4MAPTADORA3
Bicarbonate SCHEMBL1836587 0.74 PPARA (0.50) PDCD1CD274CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101687403-B Transparent hard coat film, antireflection film using the same, polarizing plate, and display device KONICA MINOLTA OPTO INC 2015-04-01 CN disclosed