SCHEMBL28006149

SCHEMBL28006149

CN1CCCC(C=O)CC1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
ACHE P22303 2/20 0.33
HTT P42858 1/20 0.33
NCF1 P14598 1/20 0.33
LMNA P02545 1/20 0.32
KAT2B Q92831 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29008606 0.98 ALDH1A1 (0.37) ALDH1A1ACHEHTTNCF1LMNA
SCHEMBL25835030 0.95 HTT (0.35) ALDH1A1HTTNCF1LMNAKDM4E
SCHEMBL464560 0.91
Hydrochloric Acid SCHEMBL28677617 0.88 NCF1 (0.37) ALDH1A1ACHEHTTNCF1
Bromide SCHEMBL29093254 0.88 NCF1 (0.37) ALDH1A1ACHENCF1
Hydrochloric Acid SCHEMBL3001802 0.88 NCF1 (0.37) ALDH1A1ACHEHTTNCF1
SCHEMBL1299314 0.82
SCHEMBL763837 0.82
SCHEMBL23741041 0.78 ALDH1A1 (0.40) ALDH1A1ACHENCF1KDM4E
SCHEMBL2240961 0.77 ALDH1A1 (0.34) ALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
CN-112920120-B Method for preparing N-methyl azepin-4-one hydrochloride 江苏凌云药业股份有限公司 2022-03-15 CN disclosed
CN-112920120-A Method for preparing N-methyl azepin-4-one hydrochloride 江苏凌云药业股份有限公司 2021-06-08 CN disclosed
CN-104449905-A Additive for reducing sulfur dioxide discharge of alcohol-based fuel SHANXI WHARTON IND CO LTD 2015-03-25 CN disclosed
CN-102316732-A Aza and [4,5-b] indole and methods of use MEDIVATION TECHNOLOGIES INC 2012-01-11 CN disclosed
CN-101243071-A 2, 4-dianilinopyrimidine derivatives, their preparation, their use as medicaments, pharmaceutical compositions and in particular as IKK inhibitors SANOFI AVENTIS (FR) 2008-08-13 CN disclosed