⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3001802 | 0.97 | NCF1 (0.37) | — | |
| Bromide SCHEMBL29093254 | 0.97 | NCF1 (0.37) | — | |
| Hydrochloric Acid SCHEMBL28677617 | 0.97 | NCF1 (0.37) | — | |
| SCHEMBL28006149 | 0.91 | ALDH1A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL29008606 | 0.89 | ALDH1A1 (0.37) | — | |
| SCHEMBL23741041 | 0.87 | ALDH1A1 (0.40) | — | |
| SCHEMBL2240961 | 0.85 | ALDH1A1 (0.34) | — | |
| SCHEMBL14683321 | 0.84 | — | — | |
| SCHEMBL25835030 | 0.84 | HTT (0.35) | — | |
| SCHEMBL14530229 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092791-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-03-21 | — | — | US | claimed |
| CN-114507184-B | Synthesis method and application of 1-methyl hexahydroazepin-4-one hydrochloride | 好医生药业集团有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117330658-A | HPLC detection method for related substances of key intermediate of lasmidbody | 福建省微生物研究所 | 2024-01-02 | — | — | CN | claimed |
| CN-116947816-A | Synthesis process of intermediate of lasmidbody | 上海迪赛诺化学制药有限公司 | 2023-10-27 | — | — | CN | claimed |
| EP-4263549-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-10-25 | — | — | EP | claimed |
| CN-116898854-A | Novel application of pyrazolopyrimidine compound | 安徽中科拓苒药物科学研究有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-111448190-B | Substituted indole compounds | 百时美施贵宝公司 | 2023-09-26 | — | — | CN | claimed |
| CN-111491930-B | Substituted Indole Compounds Useful as TLR Inhibitors | 百时美施贵宝公司 | 2023-09-26 | — | — | CN | claimed |
| CN-116568304-A | Dihydrofuranopyridine derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2023-08-08 | — | — | CN | claimed |
| CN-113866318-B | Detection method of (6-aminopyridine-2-yl) (1-methylpiperidine-4-yl) methanone dihydrochloride | 佛山奕安赛医药科技有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-103408549-A | Preparation method of alcaftadine intermediate | SUZHOU HUIHE PHARM CO LTD | 2013-11-27 | — | — | CN | claimed |
| WO-2013070657-A1 | MODULATORS OF THE G PROTEIN-COUPLED MAS RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2013-05-16 | — | — | WO | claimed |
| CN-102822152-A | Novel 1,3-oxazolidine compounds and their use as renin inhibitors | NOVADEX PHARMACEUTICALS AB | 2012-12-12 | — | — | CN | claimed |
| CN-102143953-A | Pyrimidines, triazines and their use as pharmaceutical agents | UNIV NOTTINGHAM | 2011-08-03 | — | — | CN | claimed |
| CN-101717371-A | Method for synthesizing 5-amino-6-cyano-2,4-dioxy hetero quinazoline derivatives | UNIV XUZHOU NORMAL | 2010-06-02 | — | — | CN | claimed |
| CN-1137096-C | Process for the preparation of (-) cis-3-hydroxy-1-methyl-4- (2,4, 6-trimethoxyphenyl) -piperidine | ���ĵ�˹ҩ��¹�����˾ | 2004-02-04 | — | — | CN | claimed |
| EP-0871619-B1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMA (US) | 2002-11-06 | — | — | EP | claimed |
| CN-1284065-A | Method for producing (-) Cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-piperidine | AVENTIES PHARMACEUTICAL DEUTSC (DE) | 2001-02-14 | — | — | CN | claimed |
| EP-0871619-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1998-10-21 | — | — | EP | claimed |
| WO-1997024343-A1 | PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1997-07-10 | — | — | WO | claimed |