SCHEMBL28006182

SCHEMBL28006182

CCCCc1ccccc1SOSc1ccccc1CCCC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.42
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
TYR P14679 1/20 0.39
PTGS2 P35354 3/20 0.38
ALOX5 P09917 1/20 0.38
HTR1A P08908 1/20 0.37
TLR8 Q9NR97 1/20 0.37
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
NR1H2 P55055 1/20 0.35
NR1H3 Q13133 1/20 0.35
CYSLTR2 Q9NS75 2/20 0.35
CYSLTR1 Q9Y271 2/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27869265 0.93 LIPG (0.51) LIPGCYP3A4TYRPTGS2ALOX5
SCHEMBL28006183 0.93 LIPG (0.51) LIPGCYP3A4TYRPTGS2ALOX5
SCHEMBL10881276 0.88 HTR1A (0.39) LIPGPTGS2HTR1A
SCHEMBL1576764 0.82 LIPG (0.46) LIPGCYP3A4CYP2D6CYP2C9TYR
SCHEMBL942954 0.82 APOBEC3G (0.50) LIPGCYP3A4CYP2D6CYP2C9TYR
SCHEMBL31404018 0.80 APOBEC3G (0.48) LIPGCYP3A4CYP2D6CYP2C9TYR
SCHEMBL7247417 0.79 ACHE (0.42) CYP2D6PTGS2HTR1A
SCHEMBL4381566 0.78 LIPG (0.43) LIPGCYP3A4CYP2D6CYP2C9TYR
SCHEMBL9978335 0.78 LIPG (0.43) LIPGCYP3A4CYP2D6CYP2C9TYR
SCHEMBL17707753 0.78 LIPG (0.43) LIPGCYP3A4CYP2D6CYP2C9TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843963-A Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2019-06-04 CN disclosed
CN-109790269-A Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2019-05-21 CN disclosed
CN-106008269-B Polyisocyantates composition and isocyanate polymer composition 旭化成株式会社 2018-10-19 CN disclosed
CN-107963982-A Polyisocyantates composition and isocyanate polymer composition 旭化成株式会社 2018-04-27 CN disclosed
CN-104619682-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2018-01-19 CN disclosed
CN-107056656-A Polyisocyantates composition and isocyanate polymer composition 旭化成株式会社 2017-08-18 CN disclosed
CN-104619682-A Polyisocyanate composition and isocyanate polymer composition ASAHI KASEI CHEMICALS CORP 2015-05-13 CN disclosed