Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23499947 | 0.86 | CNR2 (0.59) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL30676839 | 0.84 | NCEH1 (0.65) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL3357585 | 0.84 | NCEH1 (0.65) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL979842 | 0.84 | CA12 (0.58) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL3997233 | 0.83 | MAPT (0.55) | MAPTKDM4EHPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5403782 | 0.83 | CA12 (0.56) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL30742709 | 0.83 | MAPT (0.55) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL3915104 | 0.83 | NCEH1 (0.70) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL10617741 | 0.83 | NCEH1 (0.57) | MAPTKDM4EHPGDMEN1KMT2A | |
| SCHEMBL10966660 | 0.83 | MAPT (0.55) | MAPTKDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507913-A | Antiproliferative benzo[b]azepin-2-ones | HOFFMANN LA ROCHE | 2015-04-08 | — | — | CN | disclosed |