SCHEMBL3357585

SCHEMBL3357585

COc1ccc2ccccc2c1C(C)=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 2/20 0.65
MAPT P10636 2/20 0.56
CA9 Q16790 1/20 0.53
MTNR1A P48039 2/20 0.52
MTNR1B P49286 2/20 0.52
HPGD P15428 3/20 0.52
KDM4E B2RXH2 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
POLB P06746 1/20 0.52
PKM P14618 1/20 0.52
HTT P42858 1/20 0.52
BLM P54132 1/20 0.52
KMT2A Q03164 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CNR2 P34972 3/20 0.50
CTSD P07339 1/20 0.49
ABCG2 Q9UNQ0 1/20 0.49
CYP1A2 P05177 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30676839 1.00 NCEH1 (0.65) NCEH1MAPTCA9MTNR1AMTNR1B
SCHEMBL23499947 0.87 CNR2 (0.59) NCEH1MAPTMTNR1AMTNR1BHPGD
SCHEMBL979842 0.86 CA12 (0.58) NCEH1MAPTCA9MTNR1AMTNR1B
SCHEMBL10617741 0.84 NCEH1 (0.57) NCEH1MAPTMTNR1AMTNR1BHPGD
SCHEMBL10966660 0.84 MAPT (0.55) NCEH1MAPTMTNR1AMTNR1BHPGD
Hydrochloric Acid SCHEMBL5403782 0.84 CA12 (0.56) NCEH1MAPTCA9MTNR1AMTNR1B
SCHEMBL23930399 0.84 NCEH1 (0.72) NCEH1MAPTHPGDKDM4EALDH1A1
SCHEMBL3915104 0.84 NCEH1 (0.70) NCEH1MAPTCA9MTNR1AMTNR1B
SCHEMBL3997233 0.84 MAPT (0.55) NCEH1MAPTMTNR1AMTNR1BHPGD
SCHEMBL30742709 0.84 MAPT (0.55) NCEH1MAPTMTNR1AMTNR1BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092218-A1 USY AND RELATED ZEOLITE CATALYSTS WITH BLOCKED UNDESIRED ACTIVE SITES, AND METHODS FOR SYNTHESIZING THE SAME RELYING ON SELECTIVE EXTRACTION AND ION-EXCHANGE CHEVRON U.S.A. INC. (US) 2026-04-02 US disclosed
EP-4705240-A2 PORE EXPANSION IN MESOPOROUS Y MATERIALS The Regents of the University of California (US) 2026-03-11 EP disclosed
EP-4529493-A1 ONE-POT SYNTHESIS FOR DELAMINATED ZEOLITES Chevron U.S.A. Inc. (US) 2025-04-02 EP disclosed
CN-119255866-A One pot synthesis of layered zeolite 雪佛龙美国公司 2025-01-03 CN disclosed
US-20240367987-A1 PORE EXPANSION IN MESOPOROUS Y MATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-07 US disclosed
WO-2024228905-A2 PORE EXPANSION IN MESOPOROUS Y MATERIALS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-07 WO disclosed
US-12042788-B2 Strongly Lewis acidic metal-organic frameworks for continuous flow catalysis THE UNIVERSITY OF CHICAGO (US) 2024-07-23 US disclosed
WO-2023230093-A1 ONE-POT SYNTHESIS FOR DELAMINATED ZEOLITES CHEVRON U.S.A. INC. (US) 2023-11-30 WO disclosed
US-20230372912-A1 ONE-POT SYNTHESIS FOR DELAMINATED ZEOLITES CHEVRON U.S.A. INC. (US) 2023-11-23 US disclosed
US-20230150929-A1 SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 UNIV TEXAS (US) 2023-05-18 US disclosed
WO-1990015790-A1 IMPROVED ASYMMETRIC CATALYTIC HYDROGENATION OF ALPHA-ARYLPROPENOIC ACIDS MONSANTO COMPANY (US) 1990-12-27 WO disclosed
US-4918080-A ANXIOLYTIC AGENTS, ANTIEMETICS GLAXO GROUP LIMITED (GB) 1990-04-17 US disclosed
CN-1006386-B PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER SHINETSU CHEM IND CO (JP) 1990-01-10 CN disclosed
EP-0172427-B1 PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER Shin-Etsu Chemical Co., Ltd. (JP) 1989-07-05 EP disclosed
EP-0291172-A1 Ketone derivatives GLAXO GROUP LIMITED (GB) 1988-11-17 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
US-4577025-A Method of preparing α-aromatic propionic acids and intermediates thereof NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1986-03-18 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12042788-B2 Strongly Lewis acidic metal-organic frameworks for continuous flow catalysis CD69, TECR, MCM4 NCEH1 1317/4885MAPT 4361/4885CA9 1522/4885
US-20230150929-A1 SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 CREB1, RAPGEF4, ATF4 NCEH1 1848/4885MAPT 4881/4885CA9 4682/4885
US-20260092218-A1 USY AND RELATED ZEOLITE CATALYSTS WITH BLOCKED UNDESIRED ACTIVE SITES, AND METHODS FOR SYNTHESIZING THE SAME RELYING ON SELECTIVE EXTRACTION AND ION-EXCHANGE ACLY, HAO2, ORAI1 NCEH1 1178/4885MAPT 1891/4885CA9 64/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.