SCHEMBL3997233

SCHEMBL3997233

COc1ccc2ccccc2c1C(=O)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
KDM4E B2RXH2 2/20 0.51
HPGD P15428 2/20 0.51
LMNA P02545 2/20 0.51
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 1/20 0.51
POLB P06746 1/20 0.51
PKM P14618 1/20 0.51
HTT P42858 1/20 0.51
BLM P54132 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NCEH1 Q6PIU2 3/20 0.50
CNR2 P34972 3/20 0.49
CTSD P07339 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.48
MTNR1A P48039 2/20 0.48
MTNR1B P49286 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30742709 1.00 MAPT (0.55) MAPTKDM4EHPGDLMNAMEN1
SCHEMBL23499947 0.86 CNR2 (0.59) MAPTKDM4EHPGDLMNAMEN1
SCHEMBL3357585 0.84 NCEH1 (0.65) MAPTKDM4EHPGDLMNAMEN1
SCHEMBL979842 0.84 CA12 (0.58) MAPTKDM4EHPGDLMNAMEN1
SCHEMBL30676839 0.84 NCEH1 (0.65) MAPTKDM4EHPGDLMNAMEN1
Hydrochloric Acid SCHEMBL5403782 0.83 CA12 (0.56) MAPTKDM4EHPGDLMNAMEN1
SCHEMBL3915104 0.83 NCEH1 (0.70) MAPTKDM4EHPGDLMNAMEN1
SCHEMBL10966660 0.83 MAPT (0.55) MAPTKDM4EHPGDLMNAMEN1
SCHEMBL10617741 0.83 NCEH1 (0.57) MAPTKDM4EHPGDLMNAMEN1
SCHEMBL2113634 0.83 MAPT (0.55) MAPTKDM4EHPGDLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10345706-B2 Monomer for hardmask composition and hardmask composition including the monomer and method of forming patterns using the hardmask composition CHEIL INDUSTRIES, INC. (KR) 2019-07-09 US disclosed
US-10066057-B2 Organic layer composition, organic layer, and method of forming patterns SAMSUNG SDI CO., LTD. (KR) 2018-09-04 US disclosed
US-9665003-B2 Hardmask composition, method of forming patterns using the hardmask composition and semiconductor integrated circuit device including the patterns CHEIL INDUSTRIES, INC. (KR) 2017-05-30 US disclosed
US-9556094-B2 Monomer, hardmask composition including monomer, and method for forming pattern by using hardmask composition CHEIL INDUSTRIES, INC. (KR) 2017-01-31 US disclosed
US-20160297932-A1 ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2016-10-13 US disclosed
US-9359276-B2 Monomer for hardmask composition, hardmask composition including monomer, and pattern forming method using hardmask composition CHEIL INDUSTRIES, INC. (KR) 2016-06-07 US disclosed
US-20150274622-A1 MONOMER, HARDMASK COMPOSITION INCLUDING MONOMER, AND METHOD FOR FORMING PATTERN BY USING HARDMASK COMPOSITION CHEIL INDUSTRIES INC. (KR) 2015-10-01 US disclosed
US-8952373-B2 Hardmask composition and method of forming patterns and semiconductor integrated circuit device including the patterns CHEIL INDUSTRIES, INC. (KR) 2015-02-10 US disclosed
US-20150008212-A1 MONOMER FOR HARDMASK COMPOSITION, HARDMASK COMPOSITION INCLUDING MONOMER, AND PATTERN FORMING METHOD USING HARDMASK COMPOSITION CHEIL INDUSTRIES, INC. (KR) 2015-01-08 US disclosed
US-20150004531-A1 HARDMASK COMPOSITION, METHOD OF FORMING PATTERNS USING THE HARDMASK COMPOSITION AND SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE INCLUDING THE PATTERNS CHEIL INDUSTRIES, INC. (KR) 2015-01-01 US disclosed
US-20040048913-A1 Substituted biaryl amides as C5a receptor modulators NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) 2004-03-11 US disclosed
WO-2003082826-A1 SUBSTITUTED BIARYL AMIDES AS C5A RECEPTOR MODULATORS NEUROGEN CORPORATION (US) 2003-10-09 WO disclosed
EP-1119551-A1 NAPHTHALENECARBOXAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS AstraZeneca AB (SE) 2001-08-01 EP disclosed
WO-2000020389-A1 NAPHTHALENECARBOXAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS ASTRAZENECA AB (SE) 2000-04-13 WO disclosed
EP-0117228-B1 ANALOGS OF MEVALONOLACTONE AND DERIVATIVES THEREOF, PROCESSES FOR THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS PHARMACEUTICALS SANDOZ AG (CH) 1986-11-05 EP disclosed
EP-0117228-A1 Analogs of mevalonolactone and derivatives thereof, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals SANDOZ AG (CH) 1984-08-29 EP disclosed
WO-1984002903-A1 MEVALONOLACTONE ANALOGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS SANDOZ AG (CH) 1984-08-02 WO disclosed
US-4108877-A REACTING ACYL HALIDE WITH COPPER CYANIDE WITH HEATING IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE AND AN ORGANIC SOLVENT DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-08-22 US disclosed
US-4108875-A REACTING ACYL HALIDE WITH AN ALKALI METAL CYANIDE AND A COPPER(I) SALT IN THE PRESENCE OF A CARBOXYLIC ACID NITRILE WITH HEATING DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1978-08-22 US disclosed
US-4018767-A 5-ENDO-(1-NAPHTHOYLOXY)-N-(AMINOALKYL) BICYCLO(2.2.1)HEPTANE-2,3-DI-ENDO-CARBOXYLIC ACID IMIDES BRISTOL-MYERS COMPANY (US) 1977-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150008212-A1 MONOMER FOR HARDMASK COMPOSITION, HARDMASK COMPOSITION INCLUDING MONOMER, AND PATTERN FORMING METHOD USING HARDMASK COMPOSITION DDRGK1, MINK1, DNM1 MAPT 1466/4885KDM4E 3983/4885HPGD 3868/4885
US-20040048913-A1 Substituted biaryl amides as C5a receptor modulators C5AR1, C5AR2, C3AR1 MAPT 4555/4885KDM4E 3896/4885HPGD 2688/4885
US-10345706-B2 Monomer for hardmask composition and hardmask composition including the monomer and method of forming patterns using the hardmask composition ARCN1, DDRGK1, ACTN1 MAPT 1485/4885KDM4E 4056/4885HPGD 3872/4885
US-20150274622-A1 MONOMER, HARDMASK COMPOSITION INCLUDING MONOMER, AND METHOD FOR FORMING PATTERN BY USING HARDMASK COMPOSITION AP1M1, AP3M1, MNS1 MAPT 2147/4885KDM4E 4601/4885HPGD 3945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.