Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | CA2 | P00918 | 8/20 | 0.46 |
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759464 | 0.90 | CA12 (0.55) | CA1CA2CA12CA9TSHR | |
| SCHEMBL759467 | 0.86 | CA12 (0.61) | CA1CA2CA12CA9TSHR | |
| SCHEMBL4138078 | 0.85 | CA12 (0.62) | CA1CA2CA12CA9TSHR | |
| SCHEMBL757089 | 0.81 | TDP1 (0.47) | CA1CA2CA12CA9TSHR | |
| SCHEMBL14723706 | 0.79 | TDP1 (0.66) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18510208 | 0.79 | MAOA (0.50) | CA1CA2CA12CA9TSHR | |
| SCHEMBL18352554 | 0.78 | CA12 (0.57) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL16450357 | 0.77 | CA12 (0.54) | CA1CA2CA12CA9TDP1 | |
| SCHEMBL17884326 | 0.77 | TDP1 (0.42) | CA1CA2CA12CA9TSHR | |
| SCHEMBL8156813 | 0.76 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102460221-B | Biomedical devices | BAUSCH & LOMB | 2015-04-01 | — | — | CN | disclosed |