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SCHEMBL14723706

SCHEMBL14723706

CC(C)(C)OC(=O)NCC(=O)NCCCCCNC(=O)CNC(=O)OC(C)(C)C

nearest known ligand 0.66

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.66
▸ MAOA P21397 1/20 0.61
▸ MAOB P27338 1/20 0.61
▸ MEN1 O00255 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ GAA P10253 1/20 0.53
▸ CA1 P00915 6/20 0.53
▸ CA2 P00918 6/20 0.53
▸ CA12 O43570 5/20 0.53
▸ CA9 Q16790 5/20 0.53
▸ CYP3A4 P08684 1/20 0.44
▸ TLR2 O60603 1/20 0.43
▸ TLR1 Q15399 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ HDAC8 Q9BY41 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22929002 0.93 TDP1 (0.78) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL24096052 0.93 TDP1 (0.58) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL9017485 0.91 TDP1 (0.56) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL3311637 0.91 TDP1 (0.75) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL16909034 0.91 TDP1 (0.55) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL12984159 0.89 TDP1 (0.54) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL23571295 0.88 MAOA (0.53) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL22100906 0.86 TDP1 (0.50) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL137629 0.86 TDP1 (0.85) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL136815 0.86 TDP1 (0.85) TDP1MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170202972-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS (AL), INC. 2017-07-20 — — US disclosed
US-20160303250-A1 Subcutaneous Delivery of Poly(oxazoline) Polymer Conjugates SERINA THERAPEUTICS (AL), INC. 2016-10-20 — — US disclosed
US-20140271527-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS SERINA THERAPEUTICS, INC. (US) 2014-09-18 — — US disclosed
US-20130177521-A1 Subcutaneous Delivery of Poly(oxazoline) Conjugates SERINA THERAPEUTICS, INC. (US) 2013-07-11 — — US disclosed
US-8383093-B1 Subcutaneous delivery of poly(oxazoline) conjugates SERINA THERAPEUTICS, INC. (US) 2013-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130177521-A1 Subcutaneous Delivery of Poly(oxazoline) Conjugates OXA1L, PAICS, PAM TDP1 2428/4885MAOA 555/4885MAOB 359/4885
US-20170202972-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS CD44, CD47, LNPEP TDP1 1740/4885MAOA 2978/4885MAOB 2637/4885
US-20160303250-A1 Subcutaneous Delivery of Poly(oxazoline) Polymer Conjugates OXA1L, PAM, JMJD7 TDP1 2025/4885MAOA 531/4885MAOB 382/4885
US-20140271527-A1 SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS CD44, CD47, LNPEP TDP1 1740/4885MAOA 2978/4885MAOB 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.