SCHEMBL757089

SCHEMBL757089

C=CC(=O)OCCNC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
IDO1 P14902 2/20 0.47
CA12 O43570 4/20 0.47
CA1 P00915 4/20 0.47
CA2 P00918 4/20 0.47
CA9 Q16790 4/20 0.47
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
TSHR P16473 6/20 0.44
HPGD P15428 1/20 0.44
ALDH1A1 P00352 3/20 0.44
TP53 P04637 2/20 0.44
HIF1A Q16665 2/20 0.44
CYP3A4 P08684 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
THRB P10828 1/20 0.41
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23225393 0.91 IDO1 (0.41) TDP1IDO1CA12CA1CA2
SCHEMBL13405231 0.91 TSHR (0.56) TDP1IDO1CA12CA1CA2
SCHEMBL9966901 0.91 TSHR (0.56) TDP1IDO1CA12CA1CA2
SCHEMBL759464 0.90 CA12 (0.55) TDP1CA12CA1CA2CA9
SCHEMBL759467 0.89 CA12 (0.61) TDP1CA12CA1CA2CA9
SCHEMBL4138078 0.88 CA12 (0.62) TDP1CA12CA1CA2CA9
SCHEMBL18352704 0.86 TDP1 (0.50) TDP1IDO1CA12CA1CA2
SCHEMBL22642174 0.84 TSHR (0.40) TDP1IDO1CA12CA1CA2
SCHEMBL22143509 0.84 IDO1 (0.39) TDP1IDO1CA12CA1CA2
SCHEMBL10081623 0.82 TSHR (0.50) MEN1KMT2ATSHRHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5310795-A Impact modifiers, reaction product of carbamate functional addition polymer and modified EPDM rubber GENERAL ELECTRIC COMPANY (US) 1994-05-10 US claimed
US-20250302737-A1 POLYMERIC MICRONEEDLE ARRAYS CROSSLINKED BY PBA-DIOL COMPLEXES FOR GLUCOSE-RESPONSIVE INSULIN DELIVERY UNIV NOTRE DAME DU LAC (US) 2025-10-02 US disclosed
US-20250297149-A1 UNDERWATER ADHESIVE THE UNIVERSITY OF TOKYO (JP) 2025-09-25 US disclosed
US-12297381-B2 Laminate, release agent composition, and method for manufacturing processed semiconductor substrate NISSAN CHEMICAL CORPORATION (JP) 2025-05-13 US disclosed
US-11873426-B2 Curable composition, cured product, optical member, lens, and compound FUJIFILM CORPORATION (JP) 2024-01-16 US disclosed
US-11873426-B2 Curable composition, cured product, optical member, lens, and compound FUJIFILM CORPORATION (JP) 2024-01-16 US disclosed
US-11839657-B2 Ionizable lipids and compositions for nucleic acid delivery WESTGENE BIOPHARMA CO., LTD (CN) 2023-12-12 US disclosed
US-11839657-B2 Ionizable lipids and compositions for nucleic acid delivery WESTGENE BIOPHARMA CO., LTD (CN) 2023-12-12 US disclosed
WO-2023167269-A1 UNDERWATER ADHESIVE AGENT 国立大学法人 東京大学 2023-09-07 WO disclosed
US-20230265325-A1 LAMINATE, RELEASE AGENT COMPOSITION, AND METHOD FOR MANUFACTURING PROCESSED SEMICONDUCTOR SUBSTRATE NISSAN CHEMICAL CORPORATION (JP) 2023-08-24 US disclosed
US-6388020-B2 MODIFIED WITH LESS THAN 5% BY WEIGHT OF MONOFUNCTIONAL, DIFUNCTIONAL AND POLYFUNCTIONAL MONOMERS; IMPROVED MELT PROCESSABILITY; SHEETS, FILMS, PANELS, COATINGS, PIPES, HOLLOW OBJECTS AND FOAMS BOREALIS GMBH (AT) 2002-05-14 US disclosed
WO-2002016443-A1 NOVEL POLYMER COMPOUNDS PHAIRSON MEDICAL INC. (GB) 2002-02-28 WO disclosed
US-20010016628-A1 Modified with less than 5% by weight of monofunctional, difunctional and polyfunctional monomers; improved melt processability; sheets, films, panels, coatings, pipes, hollow objects and foams BOREALIS GMBH (AU) 2001-08-23 US disclosed
EP-0616009-B1 Elastomeric blends and method for their preparation GEN ELECTRIC (US) 1999-08-04 EP disclosed
EP-0664305-B1 Functionalized olefin polymers and polyphenylene ether compositions containing them GEN ELECTRIC (US) 1998-04-08 EP disclosed
EP-0664305-A1 Functionalized olefin polymers and polyphenylene ether compositions containing them GENERAL ELECTRIC COMPANY (US) 1995-07-26 EP disclosed
US-5380796-A Graft polymers GENERAL ELECTRIC COMPANY (US) 1995-01-10 US disclosed
EP-0616009-A2 Elastomeric blends and method for their preparation GENERAL ELECTRIC COMPANY (US) 1994-09-21 EP disclosed
US-5334659-A Improved impact strength GENERAL ELECTRIC COMPANY (US) 1994-08-02 US disclosed
US-5310795-A Impact modifiers, reaction product of carbamate functional addition polymer and modified EPDM rubber GENERAL ELECTRIC COMPANY (US) 1994-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250297149-A1 UNDERWATER ADHESIVE CDH1, EPCAM, ICAM1 TDP1 4445/4885IDO1 4031/4885CA12 723/4885
US-11839657-B2 Ionizable lipids and compositions for nucleic acid delivery POLRMT, POLN, NPC1L1 TDP1 692/4885IDO1 4835/4885CA12 1350/4885
US-11873426-B2 Curable composition, cured product, optical member, lens, and compound RB1, CCNO, SPOP TDP1 4477/4885IDO1 3699/4885CA12 1329/4885
US-20250302737-A1 POLYMERIC MICRONEEDLE ARRAYS CROSSLINKED BY PBA-DIOL COMPLEXES FOR GLUCOSE-RESPONSIVE INSULIN DELIVERY GPR119, IAPP, INSR TDP1 4741/4885IDO1 4193/4885CA12 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.