Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 4/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | SOST | Q9BQB4 | 2/20 | 0.53 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15544677 | 0.86 | RECQL (0.55) | RECQLTDP1SOSTSYNJ2APP | |
| SCHEMBL31237635 | 0.86 | RECQL (0.55) | RECQLTDP1SOSTSYNJ2APP | |
| SCHEMBL19248891 | 0.86 | RECQL (0.52) | RECQLTDP1SOSTSYNJ2APP | |
| SCHEMBL6068882 | 0.86 | CYP3A4 (0.53) | RECQLTDP1SOSTCYP3A4CYP1A2 | |
| SCHEMBL5597840 | 0.84 | CYP3A4 (0.54) | RECQLTDP1SOSTSYNJ2APP | |
| SCHEMBL5146606 | 0.79 | POLB (0.60) | RECQLTDP1CYP3A4CYP1A2HSD17B10 | |
| SCHEMBL31238336 | 0.79 | RECQL (0.56) | RECQLTDP1SOSTCYP3A4CYP1A2 | |
| SCHEMBL30754201 | 0.72 | CYP3A4 (0.51) | RECQLTDP1SOSTCYP3A4CYP1A2 | |
| SCHEMBL28763278 | 0.71 | CYP1A2 (0.51) | RECQLTDP1SOSTCYP3A4CYP1A2 | |
| SCHEMBL23044063 | 0.71 | RECQL (1.00) | RECQLTDP1SOSTSYNJ2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131193-A1 | SULFONAMIDE-CONTAINING 4-(N-METHYL) AMINOPIPERIDINE MYRICETIN DERIVATIVES, PREPARATION METHOD AND APPLICATION | GUIZHOU UNIVERSITY (CN) | 2023-04-27 | — | — | US | disclosed |
| CN-111728965-A | Application of compound in preparation of antiviral drug | 华中科技大学同济医学院附属同济医院 | 2020-10-02 | — | — | CN | disclosed |
| CN-110183430-B | 4- (N-methyl) aminopiperidine myricetin derivative containing sulfamide, preparation method and application | 贵州大学 | 2020-06-05 | — | — | CN | disclosed |
| CN-110638809-A | Composition with whitening effect | 浙江万里学院 | 2020-01-03 | — | — | CN | disclosed |
| CN-109267088-A | A kind of method of dihydromyricetin dehydrogenation | 湖南中茂生物科技有限公司 | 2019-01-25 | — | — | CN | disclosed |
| CN-109053666-A | A kind of extracting method of dihydromyricetin | 湖南中茂生物科技有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-104496955-A | Five different crystal substances of dihydromyricetin | AFFILIATED TONGJI HOSPITAL OF TONGJI MEDICAL COLLE | 2015-04-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131193-A1 | SULFONAMIDE-CONTAINING 4-(N-METHYL) AMINOPIPERIDINE MYRICETIN DERIVATIVES, PREPARATION METHOD AND APPLICATION | NISCH, SMYD2, NSD2 | RECQL 3051/4885TDP1 3144/4885SOST 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.