Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SOST | Q9BQB4 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237635 | 1.00 | RECQL (0.55) | RECQLCYP3A4HSD17B10CYP1A2KDM4E | |
| SCHEMBL6068882 | 0.89 | CYP3A4 (0.53) | RECQLCYP3A4HSD17B10CYP1A2KDM4E | |
| SCHEMBL28006751 | 0.86 | RECQL (0.55) | RECQLCYP3A4HSD17B10CYP1A2KDM4E | |
| SCHEMBL5597840 | 0.85 | CYP3A4 (0.54) | RECQLCYP3A4HSD17B10CYP1A2KDM4E | |
| SCHEMBL28763278 | 0.85 | CYP1A2 (0.51) | RECQLCYP3A4HSD17B10CYP1A2KDM4E | |
| SCHEMBL25864281 | 0.82 | CYP3A4 (0.54) | RECQLCYP3A4HSD17B10CYP1A2KDM4E | |
| SCHEMBL5146606 | 0.82 | POLB (0.60) | RECQLCYP3A4HSD17B10CYP1A2CYP19A1 | |
| SCHEMBL31238336 | 0.80 | RECQL (0.56) | RECQLCYP3A4HSD17B10CYP1A2KDM4E | |
| SCHEMBL30754201 | 0.76 | CYP3A4 (0.51) | RECQLCYP3A4HSD17B10CYP1A2KDM4E | |
| SCHEMBL31237718 | 0.73 | SLCO2B1 (0.54) | RECQLCYP3A4HSD17B10CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11878963-B2 | Semi synthetic method for dihydroquercetin | HEFEI LIFEON PHARMACEUTICAL CO., LTD. (CN) | 2024-01-23 | — | — | US | disclosed |
| US-11753389-B2 | Method for preparing dihydroquercetin | HEFEI LIFEON PHARMACEUTICAL CO., LTD. (CN) | 2023-09-12 | — | — | US | disclosed |
| US-20230192640-A1 | SEMI SYNTHETIC METHOD FOR DIHYDROQUERCETIN | HEFEI LIFEON PHARMACEUTICAL CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20230192639-A1 | METHOD FOR PREPARING DIHYDROQUERCETIN | HEFEI LIFEON PHARMACEUTICAL CO., LTD. (CN) | 2023-06-22 | — | — | US | disclosed |
| CN-109369596-B | Preparation method of taxifolin | 陕西嘉禾生物科技股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| US-20140221472-A1 | USE OF MYRICETIN OR DERIVATIVES THEREOF AS A CATHEPSIN K INHIBITOR | JILINSHENG JINZIYUAN BIOTECHNOLOGY LTD (CN) | 2014-08-07 | — | — | US | disclosed |
| EP-2762137-A1 | Use of myricetin or derivatives thereof as a cathepsin k inhibitor | Jilinsheng Jinziyuan Biotechnology Ltd. (CN) | 2014-08-06 | — | — | EP | disclosed |
| WO-2014007853-A1 | DIHYDROMYRICETIN FOR THE TREATMENT OF DISEASES AND DISORDERS OF THE GLUTAMATERGIC SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221472-A1 | USE OF MYRICETIN OR DERIVATIVES THEREOF AS A CATHEPSIN K INHIBITOR | CTSK, CTSB, CTSV | RECQL 1968/4885CYP3A4 3912/4885HSD17B10 2245/4885 |
| US-20230192639-A1 | METHOD FOR PREPARING DIHYDROQUERCETIN | QDPR, DPYD, DHODH | RECQL 70/4885CYP3A4 1214/4885HSD17B10 1019/4885 |
| US-20230192640-A1 | SEMI SYNTHETIC METHOD FOR DIHYDROQUERCETIN | QDPR, QTRT1, DHODH | RECQL 20/4885CYP3A4 283/4885HSD17B10 2290/4885 |
| US-11878963-B2 | Semi synthetic method for dihydroquercetin | QDPR, QTRT1, DHODH | RECQL 20/4885CYP3A4 283/4885HSD17B10 2290/4885 |
| US-11753389-B2 | Method for preparing dihydroquercetin | QDPR, DPYD, DHODH | RECQL 70/4885CYP3A4 1214/4885HSD17B10 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.