Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597840 | 0.90 | CYP3A4 (0.54) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL31237635 | 0.89 | RECQL (0.55) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL15544677 | 0.89 | RECQL (0.55) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL5146606 | 0.87 | POLB (0.60) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28006751 | 0.86 | RECQL (0.55) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL31238336 | 0.84 | RECQL (0.56) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL30754201 | 0.83 | CYP3A4 (0.51) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL31651095 | 0.81 | CYP3A4 (0.46) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL23752214 | 0.79 | CYP19A1 (0.51) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28625004 | 0.76 | POLB (0.59) | CYP3A4CYP19A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006024545-A1 | FUSED BICYCLIC NATURAL COMPOUNDS AND THEIR USE AS INHIBITORS OF PARP AND PARP-MEDIATED INFLAMMATORY PROCESSES | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2006-03-09 | — | — | WO | claimed |
| EP-0036117-A2 | Pressure-sensitive recording material | Spezial-Papiermaschinenfabrik August Alfred Krupp GmbH & Co (DE) | 1981-09-23 | — | — | EP | claimed |
| CN-118290503-A | Flavone glycoside compounds in golden camellia, preparation method thereof and application thereof in preparation of antitumor drugs | 广西大学 | 2024-07-05 | — | — | CN | disclosed |