Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068882 | 0.83 | CYP3A4 (0.53) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL15544677 | 0.76 | RECQL (0.55) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL31237635 | 0.76 | RECQL (0.55) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL5597840 | 0.74 | CYP3A4 (0.54) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL31238336 | 0.74 | RECQL (0.56) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL28006751 | 0.72 | RECQL (0.55) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| SCHEMBL5146606 | 0.72 | POLB (0.60) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| Naringenin SCHEMBL30266699 | 0.71 | CYP19A1 (0.71) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| Dihydrokaempferol SCHEMBL29522916 | 0.71 | CBS (0.60) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 | |
| Dihydrokaempferol SCHEMBL30311932 | 0.71 | RECQL (0.53) | CYP3A4CYP19A1CYP1A2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113322288-B | Novel flavone hydroxylase, microorganism for synthesizing flavone C-glycoside compounds and application thereof | 中国科学院分子植物科学卓越创新中心 | 2023-12-26 | — | — | CN | disclosed |