Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612514 | 0.96 | HSP90AA1 (0.48) | HSP90AA1PTPN1TLR8TLR7SMN1; SMN2 | |
| SCHEMBL5612347 | 0.82 | CASP1 (0.52) | PTPN1TLR8TLR7SMN1; SMN2CASP1 | |
| SCHEMBL28789486 | 0.82 | HSP90AA1 (0.40) | HSP90AA1PTPN1TLR8TLR7SMN1; SMN2 | |
| SCHEMBL28007126 | 0.81 | L3MBTL1 (0.47) | PTPN1TLR8TLR7SMN1; SMN2SIGMAR1 | |
| SCHEMBL29197977 | 0.79 | CASP1 (0.48) | PTPN1TLR8TLR7SIGMAR1CASP1 | |
| SCHEMBL28163103 | 0.73 | PTPN1 (0.44) | HSP90AA1PTPN1TLR8TLR7SMN1; SMN2 | |
| SCHEMBL3957743 | 0.73 | CYP1A2 (0.39) | HSP90AA1PTPN1TLR8TLR7SMN1; SMN2 | |
| SCHEMBL235080 | 0.69 | KDM4E (0.65) | SMN1; SMN2KEAP1SIGMAR1POLBKDM4E | |
| SCHEMBL30438810 | 0.69 | SMN1; SMN2 (0.42) | HSP90AA1TLR8TLR7SMN1; SMN2KEAP1 | |
| SCHEMBL946684 | 0.69 | SIGMAR1 (0.42) | SMN1; SMN2KEAP1SIGMAR1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102209714-B | Triazine, pyrimidine and pyridine analogs and their use as therapeutic agents and diagnostic probes | UNIV BASEL | 2015-03-25 | — | — | CN | disclosed |