Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28007033 | 0.87 | CSNK2A1 (0.48) | CSNK2A1CA12CA1CA2CA4 | |
| SCHEMBL10172892 | 0.84 | CSNK2A1 (0.59) | CSNK2A1TRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL7109111 | 0.83 | ACE2 (0.54) | CA12CA1CA2CA4CA6 | |
| SCHEMBL28795524 | 0.81 | KEAP1 (0.50) | CA1CA2LMNAMEN1KMT2A | |
| SCHEMBL21084977 | 0.81 | CSNK2A1 (0.55) | CSNK2A1CA12CA1CA2CA4 | |
| SCHEMBL27714381 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3930631 | 0.76 | ALDH1A1 (0.52) | CA12CA1CA2CA4CA6 | |
| SCHEMBL467550 | 0.74 | CSNK2A1 (0.68) | CSNK2A1CA12CA1CA2CA4 | |
| SCHEMBL31627797 | 0.74 | CSNK2A1 (0.68) | CSNK2A1CA12CA1CA2CA4 | |
| SCHEMBL11863770 | 0.74 | TRPA1 (0.46) | CA1CA2MAOBCA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910148-A | Aminotriazolopyridines and use thereof as kinase inhibitors | SIGNAL PHARM LLC | 2015-09-16 | — | — | CN | disclosed |
| CN-102203093-B | Aminotriazolopyridines and their use as kinase inhibitors | SIGNAL PHARM LLC | 2015-05-13 | — | — | CN | disclosed |