Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | CTSG | P08311 | 1/20 | 0.56 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193202 | 0.89 | NPC1 (0.62) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL3192014 | 0.88 | LMNA (0.77) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL19287095 | 0.87 | HDAC1 (0.63) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL3075538 | 0.87 | LMNA (0.61) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL6539681 | 0.87 | LMNA (0.51) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL8811889 | 0.86 | HDAC1 (0.66) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL9124753 | 0.86 | HDAC1 (0.66) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL6682080 | 0.86 | HDAC1 (0.66) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL9123172 | 0.86 | HDAC1 (0.66) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL18689914 | 0.86 | LMNA (0.69) | LMNAPOLBGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447688-B | Pyrazole amide compound and application thereof | 沈阳中化农药化工研发有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-104447688-A | Pyrazole amide compound and application thereof | SINOCHEM CORP | 2015-03-25 | — | — | CN | disclosed |