Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.68 |
| ▸ | CTSG | P08311 | 1/20 | 0.68 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.68 |
| ▸ | CMA1 | P23946 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL321556 | 0.93 | LMNA (0.75) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL18689914 | 0.93 | LMNA (0.69) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL9491686 | 0.91 | NPC1 (0.75) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL8779817 | 0.91 | HDAC1 (0.79) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL1754794 | 0.89 | LMNA (0.70) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL10293576 | 0.89 | LMNA (0.65) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL16248437 | 0.89 | LMNA (0.70) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL9489804 | 0.89 | HDAC1 (0.82) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL20734829 | 0.89 | HDAC1 (0.82) | LMNAPOLBGAASMN1; SMN2NPC1 | |
| SCHEMBL604217 | 0.89 | GAA (0.65) | LMNAPOLBGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666971-B2 | Amide/urea-modified liquid diphenylmethane diisocyanates | BAYER MATERIALSCIENCE LLC (US) | 2010-02-23 | — | — | US | claimed |
| US-20080139777-A1 | Amide/urea-modified liquid diphenylmethane diisocyanates | BAYER MATERIALSCIENCE LLC | 2008-06-12 | — | — | US | claimed |
| WO-2008060454-A2 | AMIDE/UREA-MODIFIED LIQUID DIPHENYLMETHANE DIISOCYANATES | BAYER MATERIALSCIENCE LLC (US) | 2008-05-22 | — | — | WO | claimed |
| EP-0447171-B1 | Polysulfate of cyclodextrin derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 1994-11-02 | — | — | EP | claimed |
| US-5248675-A | Viricides for HIV | TANABE SEIYAKU CO., LTD. | 1993-09-28 | — | — | US | claimed |
| EP-0447171-A2 | Polysulfate of cyclodextrin derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-18 | — | — | EP | claimed |
| EP-0434734-A1 | MOLDING COMPOSITIONS BASED ON POLY(1,4-CYCLOHEXYLENE DIMETHYLENE TEREPHTHALATE) CONTAINING AN AMIDE CRYSTALLIZATION AID | EASTMAN KODAK COMPANY (US) | 1991-07-03 | — | — | EP | claimed |
| WO-1990003413-A1 | MOLDING COMPOSITIONS BASED ON POLY(1,4-CYCLOHEXYLENE DIMETHYLENE TEREPHTHALATE) CONTAINING AN AMIDE CRYSTALLIZATION AID | EASTMAN KODAK COMPANY (US) | 1990-04-05 | — | — | WO | claimed |
| US-4894404-A | HEAT RESISTANCE MOLDINGS | EASTMAN KODAK COMPANY (US) | 1990-01-16 | — | — | US | claimed |
| US-20260124226-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | UNIV EMORY (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4705284-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | Emory University (US) | 2026-03-11 | — | — | EP | disclosed |
| CN-119118882-A | Olatinib intermediate and preparation method thereof and preparation method of Olatinib | 浙江荣耀生物科技股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119119055-A | Preparation method of olantinib | 浙江荣耀生物科技股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| WO-2024233354-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | EMORY UNIVERSITY (US) | 2024-11-14 | — | — | WO | disclosed |
| EP-0447171-A2 | Polysulfate of cyclodextrin derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| EP-0162663-B1 | PROCESS FOR PRODUCING HEAT-RESISTANT MOLDINGS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4894404-A | HEAT RESISTANCE MOLDINGS | EASTMAN KODAK COMPANY (US) | 1990-01-16 | — | — | US | disclosed |
| US-4663375-A | THERMOPLASTIC RESIN AND AROMATIC AMIDE | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0162663-A2 | Process for producing heat-resistant moldings | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1985-11-27 | — | — | EP | disclosed |
| US-4386053-A | IMPREGNATION OF SUBSTRATE WITH ORGANIC PEROXIDE, CHROMOGEN, BUFFER AND STABILIZER | TERUMO CORPORATION (JP) | 1983-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124226-A1 | 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO | NSUN2, SARS1, SNRPE | LMNA 1728/4885POLB 1624/4885GAA 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.