Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008156 | 0.88 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL28034976 | 0.83 | TDP1 (0.33) | TDP1 | |
| SCHEMBL28008161 | 0.79 | TDP1 (0.35) | TDP1NR1H4 | |
| SCHEMBL28008213 | 0.79 | TDP1 (0.35) | TDP1NR1H4 | |
| SCHEMBL28008146 | 0.79 | TDP1 (0.35) | TDP1NR1H4 | |
| SCHEMBL28035466 | 0.78 | CARM1 (0.32) | — | |
| SCHEMBL28035464 | 0.78 | — | — | |
| SCHEMBL27999329 | 0.73 | MAPT (0.39) | NR1H4 | |
| SCHEMBL27793390 | 0.72 | TSHR (0.41) | TDP1 | |
| SCHEMBL28039593 | 0.72 | MAOA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | disclosed |