Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27999329 | 0.85 | MAPT (0.39) | MAOAKDM4E | |
| SCHEMBL28051634 | 0.85 | FYN (0.32) | — | |
| SCHEMBL28008534 | 0.84 | NCF1 (0.44) | MAPK1KDM4E | |
| SCHEMBL27793390 | 0.83 | TSHR (0.41) | MAPK1CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL3918671 | 0.80 | TAAR1 (0.39) | — | |
| SCHEMBL27321425 | 0.80 | NPC1 (0.32) | MAOA | |
| SCHEMBL28096889 | 0.79 | CHEK2 (0.36) | MAOADYRK1ACHEK2MAPK1CYP1A2 | |
| SCHEMBL28008146 | 0.78 | TDP1 (0.35) | MAPK1 | |
| SCHEMBL28008161 | 0.78 | TDP1 (0.35) | MAPK1 | |
| SCHEMBL28008213 | 0.78 | TDP1 (0.35) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103459388-B | Novel furanone derivative | CARNA BIOSCIENCES, INC. (JP) | 2015-11-25 | — | — | CN | disclosed |