Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034975 | 0.86 | EPHX2 (0.34) | TDP1EPHX2MAPK1 | |
| SCHEMBL28008140 | 0.83 | TDP1 (0.31) | TDP1 | |
| SCHEMBL28008146 | 0.82 | TDP1 (0.35) | TDP1EPHX2MAPK1 | |
| SCHEMBL28008161 | 0.82 | TDP1 (0.35) | TDP1EPHX2MAPK1 | |
| SCHEMBL28008213 | 0.82 | TDP1 (0.35) | TDP1EPHX2MAPK1 | |
| SCHEMBL27999329 | 0.76 | MAPT (0.39) | — | |
| SCHEMBL28034969 | 0.76 | EPHX2 (0.41) | TDP1EPHX2MAPK1 | |
| SCHEMBL27793390 | 0.75 | TSHR (0.41) | TDP1MAPK1 | |
| SCHEMBL28039593 | 0.75 | MAOA (0.33) | MAPK1 | |
| SCHEMBL28035466 | 0.75 | CARM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153146-A | Novel 3-hydroxyisothiazole 1-oxide derivative | MOCHIDA PHARM CO LTD | 2015-12-16 | — | — | CN | disclosed |
| CN-103517898-B | Novel 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARMACEUTICAL CO.,LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |