Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 14/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008628 | 0.96 | MTNR1A (0.53) | L3MBTL1MTNR1AMTNR1BUSP2ALOX15 | |
| SCHEMBL9935415 | 0.88 | L3MBTL1 (0.55) | L3MBTL1MTNR1AMTNR1BUSP2ALOX15 | |
| SCHEMBL9934491 | 0.84 | MTNR1A (0.55) | L3MBTL1MTNR1AMTNR1BUSP2ALOX15 | |
| SCHEMBL9933532 | 0.82 | L3MBTL1 (0.57) | L3MBTL1MTNR1AMTNR1BUSP2ALOX15 | |
| SCHEMBL28035466 | 0.80 | CARM1 (0.32) | — | |
| SCHEMBL28035471 | 0.79 | PDK2 (0.40) | L3MBTL1PDK2 | |
| SCHEMBL28035468 | 0.79 | ALDH1A1 (0.42) | ALDH1A1LMNA | |
| SCHEMBL28008191 | 0.79 | PDE3B (0.44) | L3MBTL1PDK2ALDH1A1LMNA | |
| SCHEMBL9934283 | 0.78 | MTNR1A (0.57) | L3MBTL1MTNR1AMTNR1BUSP2ALOX15 | |
| SCHEMBL27793390 | 0.77 | TSHR (0.41) | L3MBTL1TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153146-A | Novel 3-hydroxyisothiazole 1-oxide derivative | MOCHIDA PHARM CO LTD | 2015-12-16 | — | — | CN | disclosed |
| CN-103517898-B | Novel 3-hydroxyisothiazole 1-oxide derivatives | MOCHIDA PHARMACEUTICAL CO.,LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-104710381-A | Novel 3-hydroxy-5-arylisothiazole derivative | MOCHIDA PHARM CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-102712610-B | Novel 3-hydroxy-5-arylisothiazole derivatives | MOCHIDA PHARM CO LTD | 2015-03-04 | — | — | CN | disclosed |