Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14524911 | 0.86 | CYP3A4 (0.53) | NPSR1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL27653625 | 0.83 | KMT2A (0.46) | NPSR1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL29665023 | 0.81 | TYMS (0.44) | MEN1KMT2ACYP3A4TDP1CYP1A2 | |
| SCHEMBL4084412 | 0.81 | TYMS (0.44) | MEN1KMT2ACYP3A4TDP1CYP1A2 | |
| SCHEMBL14463496 | 0.81 | MEN1 (0.43) | NPSR1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL767178 | 0.80 | MEN1 (0.63) | NPSR1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL14524866 | 0.77 | LMNA (0.40) | NPSR1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL14463542 | 0.76 | ALDH1A1 (0.60) | NPSR1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL13070218 | 0.75 | CYP1B1 (0.58) | NPSR1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL8292522 | 0.72 | SCN2A (0.62) | NPSR1MEN1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104478855-B | 3-amino-4-((E)-pyridine-2(1-hydro)-alkenyl acetonitrile)-1,8-naphthalimide derivative | 上海应用技术学院 | 2017-02-22 | — | — | CN | claimed |
| CN-104478855-A | 3-amino-4-((E)-pyridine-2(1-hydro)-alkenyl acetonitrile)-1,8-naphthalimide derivative | SHANGHAI INST TECHNOLOGY | 2015-04-01 | — | — | CN | claimed |
| CN-104478855-B | 3-amino-4-((E)-pyridine-2(1-hydro)-alkenyl acetonitrile)-1,8-naphthalimide derivative | 上海应用技术学院 | 2017-02-22 | — | — | CN | disclosed |
| CN-104478855-A | 3-amino-4-((E)-pyridine-2(1-hydro)-alkenyl acetonitrile)-1,8-naphthalimide derivative | SHANGHAI INST TECHNOLOGY | 2015-04-01 | — | — | CN | disclosed |