Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12048949 | 0.79 | MTNR1A (0.43) | MTNR1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28292859 | 0.77 | ALDH1A1 (0.42) | LMNAMAPT | |
| SCHEMBL28647947 | 0.77 | ALDH1A1 (0.42) | LMNAMAPT | |
| SCHEMBL27342036 | 0.77 | ALDH1A1 (0.42) | LMNAMAPT | |
| SCHEMBL19864956 | 0.76 | MTNR1A (0.42) | MTNR1ACRBNGRIN2DGRIN3BGRIN1 | |
| SCHEMBL2632787 | 0.74 | MTNR1A (0.43) | MTNR1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12381902 | 0.72 | MTNR1A (0.44) | MTNR1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL256377 | 0.70 | MTNR1A (0.50) | MTNR1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10094120 | 0.70 | JAK2 (0.49) | MTNR1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24897459 | 0.70 | MTNR1A (0.42) | MTNR1AGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540825-A | Azaindolines | HOFFMANN LA ROCHE | 2015-04-22 | — | — | CN | disclosed |