Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008502 | 0.81 | ERN1 (0.37) | — | |
| SCHEMBL6665599 | 0.76 | HTT (0.39) | LMNAHPGDHSD17B10HTTALDH1A1 | |
| SCHEMBL6665602 | 0.76 | HTT (0.39) | LMNAHPGDHSD17B10HTTALDH1A1 | |
| SCHEMBL28008117 | 0.75 | — | — | |
| SCHEMBL27481523 | 0.70 | — | — | |
| SCHEMBL27684065 | 0.66 | GABRA1 (0.40) | ALDH1A1 | |
| SCHEMBL28008118 | 0.64 | — | — | |
| SCHEMBL701221 | 0.64 | HPGD (0.35) | LMNAHPGDHSD17B10HTTALDH1A1 | |
| SCHEMBL7234146 | 0.64 | HPGD (0.35) | LMNAHPGDHSD17B10HTTALDH1A1 | |
| SCHEMBL701220 | 0.64 | HPGD (0.35) | LMNAHPGDHSD17B10HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104876920-A | Isooxazole compounds and intermediates thereof, and preparation method and application thereof | UNIV HENAN | 2015-09-02 | — | — | CN | claimed |
| CN-104876920-A | Isooxazole compounds and intermediates thereof, and preparation method and application thereof | UNIV HENAN | 2015-09-02 | — | — | CN | disclosed |