Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | FGF23 | Q9GZV9 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665599 | 1.00 | HTT (0.39) | HTTALOX15HPGDGFERALDH1A1 | |
| SCHEMBL10106268 | 0.81 | ALDH1A1 (0.34) | HTTALOX15HPGDGFERALDH1A1 | |
| SCHEMBL7234146 | 0.80 | HPGD (0.35) | HTTALOX15HPGDGFERALDH1A1 | |
| SCHEMBL701220 | 0.80 | HPGD (0.35) | HTTALOX15HPGDGFERALDH1A1 | |
| SCHEMBL701221 | 0.80 | HPGD (0.35) | HTTALOX15HPGDGFERALDH1A1 | |
| SCHEMBL28008503 | 0.76 | LMNA (0.32) | HTTHPGDALDH1A1MAPTLMNA | |
| SCHEMBL739510 | 0.72 | RAB9A (0.42) | HTTHPGDALDH1A1MAPTLMNA | |
| SCHEMBL29209671 | 0.72 | HPGD (0.34) | HTTALOX15HPGDGFERALDH1A1 | |
| SCHEMBL30881681 | 0.72 | HPGD (0.34) | HTTALOX15HPGDGFERALDH1A1 | |
| SCHEMBL31507613 | 0.71 | ALDH1A1 (0.44) | HTTHPGDALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131307-B1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AG (DE) | 2004-08-25 | — | — | EP | disclosed |
| US-6716989-B2 | CYCLIZATION OF A BENZYLOXIME WITH BRANCHED ALKENE OR OF A BENZALKYLALDEHYDE WITH HYDROXYLAMINE AND SULFIDING | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| US-20030229232-A1 | Herbicides | RACK MICHAEL (DE) | 2003-12-11 | — | — | US | disclosed |
| US-6603017-B2 | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6548677-B1 | Halogenating o-xylene; reacting with hydrogen peroxide and halogenating agent to form a benzyl halide; oxidation to aldehyde; oximination, cyclization, and sulfiding | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-15 | — | — | US | disclosed |
| US-20020156290-A1 | Herbicides | RACK MICHAEL (DE) | 2002-10-24 | — | — | US | disclosed |
| EP-1131307-A1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029395-A1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156290-A1 | Herbicides | CBR3, CBR1, SULT1E1 | HTT 3146/4885ALOX15 2980/4885HPGD 3739/4885 |
| US-20030229232-A1 | Herbicides | CBR3, CBR1, SULT1E1 | HTT 3158/4885ALOX15 3165/4885HPGD 3849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.