Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689335 | 1.00 | OPRD1 (0.46) | OPRD1CHRM3L3MBTL1FFAR1HTT | |
| SCHEMBL28008568 | 0.82 | CHRM3 (0.45) | OPRD1CHRM3L3MBTL1HTTCFD | |
| SCHEMBL28008567 | 0.82 | CHRM3 (0.45) | OPRD1CHRM3L3MBTL1HTTCFD | |
| SCHEMBL7021680 | 0.80 | ALDH1A1 (0.53) | OPRD1CHRM3L3MBTL1FFAR1HTT | |
| Hydrochloric Acid SCHEMBL23886299 | 0.79 | ALDH1A1 (0.51) | OPRD1CHRM3L3MBTL1FFAR1HTT | |
| SCHEMBL13683784 | 0.78 | SPHK1 (0.43) | CHRM3L3MBTL1HTTALDH1A1 | |
| SCHEMBL14530162 | 0.78 | SPHK1 (0.43) | CHRM3L3MBTL1HTTALDH1A1 | |
| SCHEMBL19903704 | 0.78 | SPHK1 (0.43) | CHRM3L3MBTL1HTTALDH1A1 | |
| SCHEMBL10808055 | 0.76 | CHRM3 (0.38) | CHRM3L3MBTL1HTT | |
| SCHEMBL10453847 | 0.76 | SLC6A9 (0.41) | CHRM3L3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104662015-A | Complement pathway modulators and uses thereof | NOVARTIS AG | 2015-05-27 | — | — | CN | disclosed |