Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14007608 | 1.00 | PELI1 (0.43) | PELI1ALOX15ALDH1A1HSD17B10TDP1 | |
| SCHEMBL3009460 | 0.86 | CYP3A4 (0.49) | ALOX15ALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL3009452 | 0.86 | CYP3A4 (0.49) | ALOX15ALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL8140673 | 0.84 | CYP1A1 (0.54) | PELI1TDP1SMN1; SMN2DDAH1SLC9A3 | |
| SCHEMBL2130414 | 0.84 | CYP1A1 (0.54) | PELI1TDP1SMN1; SMN2DDAH1SLC9A3 | |
| SCHEMBL8269471 | 0.82 | ALDH1A1 (0.42) | ALOX15ALDH1A1HSD17B10TDP1SMN1; SMN2 | |
| SCHEMBL517599 | 0.82 | PELI1 (0.46) | PELI1TDP1SMN1; SMN2DDAH1KDM4E | |
| SCHEMBL7017626 | 0.81 | MAPT (0.57) | ALDH1A1TDP1SMN1; SMN2CYP3A4THRB | |
| SCHEMBL6171189 | 0.81 | ALDH1A1 (0.50) | ALOX15ALDH1A1HSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL6171196 | 0.81 | ALDH1A1 (0.50) | ALOX15ALDH1A1HSD17B10SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101412709-B | Morpholinyl containing benzimidazoles as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD | 2015-03-25 | — | — | CN | disclosed |
| CN-101412709-A | Morpholinyl containing benzimidazoles as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD (IE) | 2009-04-22 | — | — | CN | disclosed |
| CN-1894237-A | Morpholinyl-containing benzimidazoles as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD (IE) | 2007-01-10 | — | — | CN | disclosed |