Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2130414 | 0.84 | CYP1A1 (0.54) | PELI1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL11837763 | 0.84 | CA1 (0.56) | CHRNA7TYRLMNAMAPTKDM4E | |
| SCHEMBL8140673 | 0.84 | CYP1A1 (0.54) | PELI1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL31683137 | 0.84 | CA1 (0.56) | CHRNA7TYRLMNAMAPTKDM4E | |
| SCHEMBL28008787 | 0.82 | PELI1 (0.43) | PELI1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL14007608 | 0.82 | PELI1 (0.43) | PELI1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL617300 | 0.81 | CHRNA7 (0.64) | PELI1CHRNA7TYR | |
| SCHEMBL617301 | 0.81 | CHRNA7 (0.64) | PELI1CHRNA7TYR | |
| SCHEMBL26316886 | 0.81 | NFE2L2 (0.47) | PELI1DDAH1 | |
| SCHEMBL10190857 | 0.80 | TRPA1 (0.56) | TYRTRPA1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4066085-A | — | — | None | — | — | JP | disclosed |
| US-12246014-B2 | Azetidine derivatives | LIGAND UK DEVELOPMENT LIMITED (GB) | 2025-03-11 | — | — | US | disclosed |
| US-10918640-B2 | Azetidine derivatives | VERNALIS (R&D) LTD. (GB) | 2021-02-16 | — | — | US | disclosed |
| US-10383871-B2 | Azetidine derivatives | VERNALIS (R&D) LTD. (GB) | 2019-08-20 | — | — | US | disclosed |
| US-20170196864-A1 | Azetidine Derivatives | VERNALIS DEVELOPMENT LIMITED (GB) | 2017-07-13 | — | — | US | disclosed |
| US-9475800-B2 | Azetidine derivatives | VERNALIS (R&D) LTD. (GB) | 2016-10-25 | — | — | US | disclosed |
| EP-2265578-B1 | AZETIDINE DERIVATIVES | VERNALIS R&D LTD (GB) | 2015-09-16 | — | — | EP | disclosed |
| US-20150183769-A1 | Azetidine Derivatives | VERNALIS DEVELOPMENT LIMITED (GB) | 2015-07-02 | — | — | US | disclosed |
| US-9006269-B2 | Azetidine derivatives | VERNALIS (R&D) LTD. (GB) | 2015-04-14 | — | — | US | disclosed |
| US-8884020-B2 | Indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2014-11-11 | — | — | US | disclosed |
| US-20070155707-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | KADMUS PHARMACEUTICALS, INC. (US) | 2007-07-05 | — | — | US | disclosed |
| WO-2007022501-A2 | USEFUL INDOLE COMPOUNDS | MICROBIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| EP-0905142-B1 | Inhibitors against prostate-specific antigen | JAPAN CHEM RES (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6284734-B1 | NONAPEPTIDE | JCR PHARMACEUTICALS CO., LTD. (JP) | 2001-09-04 | — | — | US | disclosed |
| EP-0905142-A1 | Inhibitors against prostate-specific antigen | JCR PHARMACEUTICALS CO., LTD. (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5750650-A | AQUEOUS EXTRACT OF CULTURE OF BACILLUS | HONDA TRADING CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| JP-H0466085-A | PROLYL ENDOPERPTIDASE AND PRODUCTION THEREOF | YAKULT HONSHA CO LTD | 1992-03-02 | — | — | JP | disclosed |
| EP-0080649-B1 | METHOD FOR DETERMINING BACTERIAL ENDOTOXIN AND KIT THEREFOR | Seikagaku Kogyo Co. Ltd. (JP) | 1985-08-07 | — | — | EP | disclosed |
| US-4495294-A | AMOEBOCYTE LYSATE COMPONENT TREATED WITH ACID | SEIKAGAKU KOGYO CO., LTD. (JP) | 1985-01-22 | — | — | US | disclosed |
| EP-0080649-A1 | Method for determining bacterial endotoxin and kit therefor | Seikagaku Kogyo Co. Ltd. (JP) | 1983-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10918640-B2 | Azetidine derivatives | FAAH2, FAAH, APEH | PELI1 2873/4885CHRNA7 1442/4885TYR 769/4885 |
| US-12246014-B2 | Azetidine derivatives | FAAH2, FAAH, APEH | PELI1 2686/4885CHRNA7 1495/4885TYR 1071/4885 |
| US-20150183769-A1 | Azetidine Derivatives | FAAH2, FAAH, APEH | PELI1 3021/4885CHRNA7 1408/4885TYR 734/4885 |
| US-20070155707-A1 | IONIZABLE INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, NAAA | PELI1 3488/4885CHRNA7 1341/4885TYR 3401/4885 |
| US-20170196864-A1 | Azetidine Derivatives | FAAH2, FAAH, APEH | PELI1 2873/4885CHRNA7 1442/4885TYR 769/4885 |
| US-10383871-B2 | Azetidine derivatives | FAAH2, FAAH, APEH | PELI1 2873/4885CHRNA7 1442/4885TYR 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.