Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954918 | 0.85 | MAPT (0.49) | CHRNB2CHRNA4LMNAMAPTKMT2A | |
| SCHEMBL17046368 | 0.81 | TSHR (0.44) | CHRNB2CHRNA4LMNAALDH1A1MAPT | |
| SCHEMBL16950939 | 0.81 | CHRNB2 (0.41) | CHRNB2CHRNA4LMNAALDH1A1MAPT | |
| SCHEMBL16956571 | 0.81 | MAPT (0.51) | CHRNB2CHRNA4LMNAALDH1A1MAPT | |
| SCHEMBL6834623 | 0.80 | LMNA (0.50) | LMNAALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL30833154 | 0.79 | CHRNB2 (0.68) | CHRNB2CHRNA4LMNAALDH1A1MAPT | |
| SCHEMBL18677858 | 0.79 | TSHR (0.53) | CHRNB2CHRNA4LMNAALDH1A1MAPT | |
| SCHEMBL3460244 | 0.79 | CHRNB2 (0.68) | CHRNB2CHRNA4LMNAALDH1A1MAPT | |
| SCHEMBL15156144 | 0.78 | MAPT (0.56) | CHRNB2CHRNA4LMNAALDH1A1MAPT | |
| SCHEMBL15155997 | 0.78 | S1PR4 (0.41) | CHRNB2CHRNA4LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640861-A | Purinone compounds as kinase inhibitors | PHARMACYCLICS INC | 2015-05-20 | — | — | CN | disclosed |