Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27551163 | 0.94 | ITGB3 (0.43) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL760154 | 0.86 | ITGB3 (0.38) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL19834800 | 0.83 | ITGB3 (0.43) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL16213225 | 0.82 | ITGB3 (0.47) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL27793328 | 0.81 | GNAI3 (0.53) | ITGB3ITGA2BGNAI3GNAO1GNAI1 | |
| SCHEMBL19834792 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL3980000 | 0.81 | SIGMAR1 (0.47) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL1840437 | 0.81 | ITGB3 (0.44) | ITGB3ITGA2BHDAC3HDAC4HDAC1 | |
| SCHEMBL7452238 | 0.80 | ITGB3 (0.63) | ITGB3ITGA2BNAMPTGNAI3GNAO1 | |
| Bicarbonate SCHEMBL1720860 | 0.80 | KDM5A (0.42) | PKMMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104530048-A | Novel adenine derivatives | GLAXOSMITHKLINE LLC | 2015-04-22 | — | — | CN | disclosed |