Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798481 | 0.91 | ADORA3 (0.42) | ADORA1ADORA3ADORA2AKDM4ESMN1; SMN2 | |
| SCHEMBL2801112 | 0.87 | CYP3A4 (0.35) | ADORA1ADORA3ADORA2APDE4BKDM4E | |
| SCHEMBL2801294 | 0.86 | CCNA2 (0.46) | ADORA1ADORA3ADORA2AADORA2BCCNA2 | |
| SCHEMBL2800907 | 0.85 | CCNA2 (0.54) | ADORA1ADORA3ADORA2AADORA2BCCNA2 | |
| SCHEMBL2800801 | 0.81 | ADORA1 (0.45) | ADORA1CCNA2CDK2RAB9ANPSR1 | |
| SCHEMBL2801694 | 0.80 | CCNA2 (0.44) | ADORA1ADORA3ADORA2AADORA2BCCNA2 | |
| SCHEMBL2801494 | 0.78 | CCNA2 (0.57) | ADORA1ADORA3ADORA2AADORA2BCCNA2 | |
| SCHEMBL2800936 | 0.78 | STAT6 (0.42) | ADORA1ADORA3ADORA2A | |
| SCHEMBL2798414 | 0.78 | STAT6 (0.43) | ADORA1ADORA3ADORA2ARAB9ANPC1 | |
| SCHEMBL2800990 | 0.78 | AXL (0.42) | NPSR1PDE4BMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206714-B1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | KYOWA HAKKO KIRIN CO LTD (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-8729264-B2 | Agent for prevention and/or treatment of skin diseases | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20100256134-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2206714-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2010-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256134-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | TYR, CUTA, SERPINB1 | ADORA1 2960/4885ADORA3 3783/4885ADORA2A 4017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.