SCHEMBL2800949

SCHEMBL2800949

OC1(Br)CC=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31186268 1.00 KDM4E (0.34) KDM4EPKM
SCHEMBL556904 0.79 KDM4E (0.36) KDM4EPKM
SCHEMBL5701610 0.79 KDM4E (0.36) KDM4EPKM
SCHEMBL28499627 0.76 KDM4E (0.38) KDM4EPKM
SCHEMBL7064134 0.76 KDM4E (0.34) KDM4EPKM
SCHEMBL5159548 0.76 KDM4E (0.34) KDM4EPKM
SCHEMBL3860686 0.76 CA1 (0.31)
SCHEMBL6544873 0.74 ADAMTS4 (0.31)
SCHEMBL8817458 0.74 KDM4E (0.37) KDM4EPKM
SCHEMBL8205643 0.74 KDM4E (0.37) KDM4EPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118894886-A Preparation method of axial chiral alkenyl borate containing phosphine or carboxylate 福州大学 2024-11-05 CN disclosed
EP-4325210-A1 COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE FUJIFILM Corporation (JP) 2024-02-21 EP disclosed
US-20240043742-A1 COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE FUJIFILM CORPORATION (JP) 2024-02-08 US disclosed
CN-112430234-B Novel KRAS G12C protein inhibitor and preparation method and application thereof 信达生物制药(苏州)有限公司 2023-04-28 CN disclosed
WO-2022220288-A1 COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE 富士フイルム株式会社 2022-10-20 WO disclosed
EP-3366750-B1 STABILIZER AND STABILIZATION METHOD FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2021-07-21 EP disclosed
US-10961185-B2 Stabilizer and stabilization method FUJIFILM WAKO PURE CHEMICAL CHEMICAL CORPORATION (JP) 2021-03-30 US disclosed
CN-112430234-A Novel KRAS G12C protein inhibitor and preparation method and application thereof 信达生物制药(苏州)有限公司 2021-03-02 CN disclosed
CN-108138047-B Stabilizer and stabilization method 富士胶片和光纯药株式会社 2021-02-09 CN disclosed
WO-2020184625-A1 GRAPHENE NANORIBBON AND METHOD FOR PRODUCING SAME 国立大学法人東海国立大学機構 2020-09-17 WO disclosed
CN-110452167-B Quinoline derivatives, preparation method and application thereof 东莞市东阳光农药研发有限公司 2020-08-21 CN disclosed
CN-110452167-A Quinoline derivatives and its preparation method and application DONGGUAN HEC PESTICIDE RES AND DEVELOPMENT CO LTD 2019-11-15 CN disclosed
CN-109081310-A A method of extracting bromine from brominated feed liquid or waste water 山东省海洋化工科学研究院 2018-12-25 CN disclosed
US-20180290969-A1 STABILIZER AND STABILIZATION METHOD FUJIFILM WAKO PURE CHEMICAL CHEMICAL CORPORATION (JP) 2018-10-11 US disclosed
EP-3366750-A1 STABILIZER AND STABILIZATION METHOD FUJIFILM Wako Pure Chemical Corporation (JP) 2018-08-29 EP disclosed
CN-108138047-A STABILIZER AND STABILIZATION METHOD 和光纯药工业株式会社 2018-06-08 CN disclosed
US-9309174-B2 Polycyclic ring assembly compound and organic electroluminescent device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2016-04-12 US disclosed
US-20100187512-A1 POLYCYCLIC RING ASSEMBLY COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD (JP) 2010-07-29 US disclosed
US-7109225-B2 Antidiabetic agents; hypotensive agents; anticholesterol agents; antilipemic agents; antiinflammatory agents; antiproliferative agents HOFMANN-LA ROCHE INC. (US) 2006-09-19 US disclosed
US-20040157898-A1 Novel substituted oxazole derivatives F. HOFFMANN-LA ROCHE AG (CH) 2004-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180290969-A1 STABILIZER AND STABILIZATION METHOD H1-0, H1-2, H1-4 KDM4E 1253/4885PKM 2289/4885
US-20040157898-A1 Novel substituted oxazole derivatives OXA1L, SLC5A1, GPR119 KDM4E 2839/4885PKM 1209/4885
US-10961185-B2 Stabilizer and stabilization method H1-0, H1-2, H1-4 KDM4E 1253/4885PKM 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.