Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 4/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204695 | 0.86 | TRPV4 (0.44) | TRPV4PDE2A | |
| SCHEMBL28009191 | 0.86 | P2RX7 (0.45) | TRPV4P2RX7KCNK3 | |
| SCHEMBL12204706 | 0.85 | TRPV4 (0.43) | TRPV4P2RX7 | |
| SCHEMBL12204643 | 0.81 | TRPV4 (0.40) | TRPV4P2RX7TRPV3PDE2A | |
| SCHEMBL12230273 | 0.81 | S1PR1 (0.40) | TRPV4 | |
| SCHEMBL2609310 | 0.80 | TRPV4 (0.52) | TRPV4P2RX7TRPV3PDE2A | |
| SCHEMBL19773439 | 0.77 | TRPV4 (0.48) | TRPV4P2RX7TRPV3PDE2A | |
| SCHEMBL367869 | 0.77 | TRPV4 (0.48) | TRPV4P2RX7TRPV3PDE2A | |
| SCHEMBL13745241 | 0.77 | TRPV4 (0.48) | TRPV4P2RX7TRPV3PDE2A | |
| SCHEMBL21346253 | 0.77 | TRPV4 (0.48) | TRPV4P2RX7TRPV3PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884445-B | Benzamide | H.隆德贝克有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-104884445-A | Benzamides | LUNDBECK & CO AS H | 2015-09-02 | — | — | CN | disclosed |