Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204695 | 0.86 | TRPV4 (0.44) | TRPV4CYP2C9 | |
| SCHEMBL28009682 | 0.86 | TRPV4 (0.44) | P2RX7TRPV4KCNK3 | |
| SCHEMBL12204706 | 0.85 | TRPV4 (0.43) | P2RX7TRPV4 | |
| SCHEMBL12204643 | 0.81 | TRPV4 (0.40) | P2RX7TRPV4GPR139IDH1CYP2C9 | |
| SCHEMBL12230273 | 0.81 | S1PR1 (0.40) | TRPV4 | |
| SCHEMBL2609310 | 0.80 | TRPV4 (0.52) | P2RX7TRPV4GPR139CYP2C9 | |
| SCHEMBL14033441 | 0.79 | SMN1; SMN2 (0.49) | P2RX7TRPV4ATMHDAC4 | |
| SCHEMBL14033326 | 0.79 | P2RX7 (0.48) | P2RX7TRPV4ATMHDAC4KDM1A | |
| SCHEMBL16462564 | 0.77 | P2RX7 (0.52) | P2RX7TRPV4KDM1AMAOAMAOB | |
| SCHEMBL998305 | 0.77 | TRPV4 (0.48) | P2RX7TRPV4GPR139CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884445-B | Benzamide | H.隆德贝克有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-104884445-A | Benzamides | LUNDBECK & CO AS H | 2015-09-02 | — | — | CN | disclosed |