Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355866 | 0.70 | CCNA2 (0.31) | BCAT2 | |
| SCHEMBL15898496 | 0.67 | GRM4 (0.38) | BCAT2 | |
| SCHEMBL5508581 | 0.64 | BCAT2 (0.42) | BCAT2 | |
| SCHEMBL5508575 | 0.64 | BCAT2 (0.42) | BCAT2 | |
| SCHEMBL8773089 | 0.63 | — | — | |
| SCHEMBL85277 | 0.63 | — | — | |
| SCHEMBL3958662 | 0.63 | — | — | |
| SCHEMBL2616826 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL21598415 | 0.61 | LMNA (0.35) | BCAT2 | |
| SCHEMBL3908932 | 0.61 | TDP1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103313978-B | Pyrazole aminopyrimidine derivatives as LRRK2 modulators | HOFFMANN LA ROCHE | 2015-04-15 | — | — | CN | disclosed |