Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28347463 | 0.80 | KMT2A (0.53) | KMT2ARAB9ANPC1NR1I2LMNA | |
| SCHEMBL22640298 | 0.77 | MLYCD (0.64) | KMT2ARAB9ANPC1AHRMEN1 | |
| SCHEMBL1663048 | 0.74 | RAB9A (0.59) | KMT2ARAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL2686342 | 0.70 | KMT2A (0.54) | KMT2ARAB9ANPC1TP53MEN1 | |
| SCHEMBL4061093 | 0.70 | NPC1 (0.66) | KMT2ARAB9ANPC1LMNATP53 | |
| SCHEMBL22441291 | 0.70 | NPC1 (0.60) | KMT2ARAB9ANPC1LMNASMN1; SMN2 | |
| SCHEMBL5674883 | 0.69 | EPHX1 (0.48) | KMT2ARAB9ALMNATP53EPHX1 | |
| SCHEMBL8349329 | 0.69 | HDAC1 (0.70) | RAB9ANPC1 | |
| SCHEMBL2732773 | 0.69 | HPGD (0.70) | KMT2ARAB9ANPC1LMNAEPHX1 | |
| SCHEMBL1065454 | 0.69 | F10 (0.49) | KMT2ARAB9ANPC1RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985402-B | Tranylcypromine derivatives as inhibitors of histone demethylase LSD1 and/or LSD2 | UNIV ROMA | 2015-04-29 | — | — | CN | disclosed |