Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16508030 | 0.86 | ALDH1A1 (0.41) | HPGDSMN1; SMN2 | |
| SCHEMBL23458022 | 0.85 | RAPGEF4 (0.39) | RAPGEF4ABCB1HPGDCA1CA2 | |
| SCHEMBL23458023 | 0.85 | RAPGEF4 (0.39) | RAPGEF4ABCB1HPGDCA1CA2 | |
| SCHEMBL699401 | 0.79 | RAPGEF4 (0.43) | RAPGEF4ABCB1HPGDCA1CA2 | |
| SCHEMBL699400 | 0.79 | RAPGEF4 (0.43) | RAPGEF4ABCB1HPGDCA1CA2 | |
| SCHEMBL25004978 | 0.78 | MAPT (0.34) | HPGDKMT2A | |
| Ammonia Solution, Strong SCHEMBL1984066 | 0.76 | RAPGEF4 (0.41) | RAPGEF4ABCB1HPGDCA1CA2 | |
| SCHEMBL28401870 | 0.76 | ABCB1 (0.37) | RAPGEF4ABCB1HPGDCA1CA2 | |
| SCHEMBL293077 | 0.76 | RAPGEF4 (0.33) | RAPGEF4ABCB1HPGDCA1CA2 | |
| SCHEMBL28486590 | 0.76 | RAPGEF4 (0.33) | RAPGEF4ABCB1HPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102918089-B | Method for obtaining a rubber composition including a thermoplastic filler | MICHELIN SOC TECH | 2015-03-18 | — | — | CN | disclosed |