Malonic Acid

Malonic Acid

SCHEMBL28010899

C1CCCC1.C1CCCC1.O=C(O)CC(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.75
SRR Q9GZT4 1/20 0.75
FFAR3 O14843 1/20 0.47
LMNA P02545 3/20 0.40
EGLN1 Q9GZT9 2/20 0.40
ALKBH5 Q6P6C2 1/20 0.40
SUCNR1 Q9BXA5 1/20 0.40
CYP2C19 P33261 2/20 0.39
ALDH1A1 P00352 2/20 0.39
TSHR P16473 4/20 0.38
GLRA1 P23415 1/20 0.38
SLC6A9 P48067 1/20 0.38
OR51E2 Q9H255 1/20 0.38
KDM4E B2RXH2 2/20 0.36
CYP1A2 P05177 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MAPK1 P28482 1/20 0.36
USP2 O75604 1/20 0.36
BLM P54132 1/20 0.36
CACNA2D1 P54289 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL28796740 1.00 LDHA (0.75) LDHASRRFFAR3LMNAEGLN1
Malonic Acid SCHEMBL1727482 1.00 LDHA (0.75) LDHASRRFFAR3LMNAEGLN1
Malonic Acid SCHEMBL28318741 1.00 LDHA (0.75) LDHASRRFFAR3LMNAEGLN1
Malonic Acid SCHEMBL27594169 0.96 LDHA (0.69) LDHASRRFFAR3LMNAEGLN1
Malonic Acid SCHEMBL28289299 0.93 LDHA (0.64) LDHASRRFFAR3LMNAEGLN1
Malonic Acid SCHEMBL23831 0.87 LDHA (1.00) LDHASRRFFAR3LMNAEGLN1
Malonic Acid SCHEMBL336 0.87
Malonic Acid SCHEMBL1332554 0.87
Malonic Acid SCHEMBL1332587 0.87
Malonic Acid SCHEMBL3358611 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104434927-A Application of bicyclopentanoperhydrophenanthrene malonate B in preparing hypotensive drugs UNIV JILIN AGRICULTURAL 2015-03-25 CN disclosed