Malonic Acid

Malonic Acid

SCHEMBL28289299

C1CCCCC1.CO.CO.O=C(O)CC(=O)O

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.64
SRR Q9GZT4 1/20 0.64
FFAR3 O14843 2/20 0.50
CYP2C19 P33261 1/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 3/20 0.35
EGLN1 Q9GZT9 2/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
SUCNR1 Q9BXA5 1/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
TSHR P16473 5/20 0.33
CYP1A2 P05177 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 2/20 0.33
GLRA1 P23415 1/20 0.33
SLC6A9 P48067 1/20 0.33
OR51E2 Q9H255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL28010899 0.93 LDHA (0.75) LDHASRRFFAR3CYP2C19ALDH1A1
Malonic Acid SCHEMBL28796740 0.93 LDHA (0.75) LDHASRRFFAR3CYP2C19ALDH1A1
Malonic Acid SCHEMBL1727482 0.93 LDHA (0.75) LDHASRRFFAR3CYP2C19ALDH1A1
Malonic Acid SCHEMBL28318741 0.93 LDHA (0.75) LDHASRRFFAR3CYP2C19ALDH1A1
Malonic Acid SCHEMBL27594169 0.89 LDHA (0.69) LDHASRRFFAR3CYP2C19ALDH1A1
Malonic Acid SCHEMBL782125 0.89
Malonic Acid SCHEMBL28315857 0.87 LDHA (0.56) LDHASRRFFAR3CYP2C19ALDH1A1
Malonic Acid SCHEMBL6843425 0.85 LDHA (0.75) LDHASRRFFAR3LMNAEGLN1
Acetoacetic Acid SCHEMBL2525168 0.84 KDM4E (0.46) LDHASRRFFAR3CYP2C19ALDH1A1
Propionic Acid SCHEMBL29144978 0.81 FFAR3 (0.77) LDHASRRFFAR3CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791381-A Electrophotographic photoreceptor, and electrophotographic process cartridge and image forming apparatus containing the same 三菱化学株式会社 2019-05-21 CN disclosed