Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881545 | 0.73 | MAPT (0.47) | SLC6A4LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL433303 | 0.73 | SLC6A4 (0.50) | SLC6A4LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL433304 | 0.73 | SLC6A4 (0.50) | SLC6A4LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL28035599 | 0.72 | MAOB (0.47) | LMNAKMT2AL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11611383 | 0.71 | SLC6A4 (0.54) | SLC6A4LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL28158105 | 0.70 | MMP1 (0.49) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5799253 | 0.70 | MMP1 (0.49) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5799249 | 0.70 | MMP1 (0.49) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5415017 | 0.70 | KMT2A (0.40) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28771086 | 0.70 | ALDH1A1 (0.47) | LMNAKMT2AL3MBTL1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103237795-B | Substituted oxadiazole compounds and their use as S1P1Use of agonists | BRISTOL-MYERS SQUIBB CO. (US) | 2015-10-21 | — | — | CN | disclosed |
| CN-103124727-B | Substituted 3-phenyl-1,2,4-oxadiazole compounds | BRISTOL MYERS SQUIBB CO | 2015-03-25 | — | — | CN | disclosed |